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SION · Sionna Therapeutics, Inc.
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TEAM-0.32% 13F +439META+2.47% 13F +2,694RCG-2.04% CLUSTERUTHR-4.03% 13F +425CRWV-1.12% 13F +693CRM-0.46% 13F +1,018CVNA+2.74% 13F +794TPL-0.71% 13F +444NET-4.47% 13F +710MSTR-1.35% 13F +526DELL+15.81% 13F +1,203CRWD-5.42% 13F +1,382ANET+2.87% 13F +1,323COIN-1.05% 13F +475TEAM-0.32% 13F +439META+2.47% 13F +2,694RCG-2.04% CLUSTERUTHR-4.03% 13F +425CRWV-1.12% 13F +693CRM-0.46% 13F +1,018CVNA+2.74% 13F +794TPL-0.71% 13F +444NET-4.47% 13F +710MSTR-1.35% 13F +526DELL+15.81% 13F +1,203CRWD-5.42% 13F +1,382ANET+2.87% 13F +1,323COIN-1.05% 13F +475
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SION

Sionna Therapeutics, Inc.
PHARMA & BIOTECH · PHARMACEUTICAL PREPARATIONS · CIK 0002036042
FORM 144 · 1☆ WATCH
INSIDER NET · 180D
-$96.3M
open-market buys minus sells, Form 4 codes P and S
INSIDER BUYERS · 180D
0
CONGRESS BUYERS · 1Y
0
FUNDS ADDED · QTR
92
13F, latest reported quarter
REVENUE GROWTH
-
XBRL, annual
NET MARGIN
-
CONVERSIONS · 180D
1
codes C/M, not in net · $62.6K priced
SEVEN FACTS, RANKED AGAINST THE SECTOR · RANK IS NOT A FORECAST
INSIDERS
net -$96.3M over 180 days
-$18.7M over 90 days
below 97% of Pharma & Biotech
CONGRESS
no member of Congress has reported trading it
FUNDS
92 funds added or opened last quarter
more than 62% of Pharma & Biotech
REVENUE
no revenue reported in any filing
MARGIN
no margin: this company reports no revenue to divide by
BUYBACKS
no share repurchases reported
SHORT
no short interest reported
THE SITUATION · EVERY LINE IS ONE RULE OVER ONE DATASET
Insiders are net sellers: -$96.3M across 3 people in 180 days.
92 funds added or opened positions in the latest 13F quarter, of 149 holders.
The year, with the filings on it
Total return indexed to 100 over the last 12 months · every marker is a federal filing, placed at its date — hover any marker for the detail
TOTAL 12M RETURN -71.2%
-71.2%12M
-82%-21%+40%+101%2025-092025-102025-122026-032026-052026-072026-09 2026-04-15 · Thompson Peter A. sold $10.5M2026-04-15 · ORBIMED ADVISORS LLC sold $10.5M2026-04-16 · Thompson Peter A. sold $10.3M2026-04-16 · ORBIMED ADVISORS LLC sold $10.3M2026-01-22 · WINKELRIED JON sold $10.0M2026-05-11 · Thompson Peter A. sold $8.5M2026-05-11 · ORBIMED ADVISORS LLC sold $8.5M2026-06-30 · ORBIMED ADVISORS LLC sold $5.3M2026-06-30 · Thompson Peter A. sold $5.3M2025-10-24 · RA Capital Nexus Fund III, L.P. sold $4.8M2025-10-24 · RA Capital Nexus Fund III, L.P. sold $4.3M2025-11-24 · ORBIMED ADVISORS LLC sold $4.2M2025-11-24 · Thompson Peter A. sold $4.2M2026-07-07 · ORBIMED ADVISORS LLC sold $3.9M2026-07-07 · Thompson Peter A. sold $3.9M2026-05-08 · Thompson Peter A. sold $2.7M2026-05-08 · ORBIMED ADVISORS LLC sold $2.7M2025-10-24 · RA Capital Nexus Fund III, L.P. sold $2.6M2025-10-16 · Booth Bruce sold $2.4M2026-04-17 · Thompson Peter A. sold $2.3M2026-04-17 · ORBIMED ADVISORS LLC sold $2.3M2026-05-07 · Thompson Peter A. sold $2.2M2026-05-07 · ORBIMED ADVISORS LLC sold $2.2M2026-04-14 · Thompson Peter A. sold $2.1M2026-04-14 · ORBIMED ADVISORS LLC sold $2.1M2025-10-15 · Booth Bruce sold $2.0M2025-09-29 · Booth Bruce sold $1.6M2025-12-24 · OrbiMed Capital GP VIII LLC sold $1.5M2025-12-24 · Thompson Peter A. sold $1.5M2025-10-16 · Booth Bruce sold $1.4M2025-10-13 · Booth Bruce sold $1.3M2026-02-03 · Thompson Peter A. sold $1.3M2026-02-03 · OrbiMed Capital GP VIII LLC sold $1.3M2025-10-21 · Cloonan Michael sold $1.3M2025-10-28 · RA Capital Nexus Fund III, L.P. sold $1.2M2025-10-21 · Cloonan Michael sold $1.1M2025-10-03 · Booth Bruce sold $935.9K2025-10-15 · Booth Bruce sold $934.6K2025-10-17 · Booth Bruce sold $925.2K2025-10-21 · Booth Bruce sold $903.9K2025-10-21 · Cloonan Michael sold $838.0K2025-10-20 · Booth Bruce sold $833.7K2026-07-06 · JENNIFER FITZPATRICK filed to sell $450.9K
INSIDER SELLFORM 144
INDEXED RETURN, DIVIDEND-ADJUSTED — NOT A PRICE CHART · LARGE TRADES DRAWN FIRST WHEN A NAME FILES HEAVILY
Live price
Daily candles from TradingView, on their licence — no filings are marked on this one
WHY THIS NAME IS ON THE DESK
Insiders have filed to sell — before selling.
The record shows a net $96.3M sold by insiders over 180 days, 92 funds added last quarter, $450.9K in planned Form 144 sales. Every figure is a federal filing, dated the day it became public.
Backtest this pattern Open the screener
Same sector, ranked by filing activity
Sector from the SEC's own SIC classification
UTHRCPIXMRNAREGNLLYALNYELFCITRMDGLDNAVRTXNUVL
Insider transactions
Form 4 purchases and sales (codes P and S) — grants, option exercises and preferred conversions excluded

Over the last 180 days, Sionna Therapeutics, Inc. insiders sold a net $96.3M of stock across 166 Form 4 purchases and sales, with 0 insider(s) buying. Source: SEC Form 4 filings, as of 2026-09-04.

INSIDER
FILED
SHARES
VALUE
ORBIMED ADVISORS LLC
Director
SELL
2026-07-07
85,918.0
$3.9M
Thompson Peter A.
Director
SELL
2026-07-07
85,918.0
$3.9M
Fitzpatrick Jennifer
Chief Legal Officer
SELL
2026-07-06
10,250.0
$446.9K
ORBIMED ADVISORS LLC
Director
SELL
2026-06-30
115,844.0
$5.3M
Thompson Peter A.
Director
SELL
2026-06-30
115,844.0
$5.3M
166 TRANSACTIONS ON RECORD

Showing the most recent few. Create a free account to see 161 more transactions on record, the cross-source screener and CSV export. We store only your email address, and there is no password to create.

Institutional holders
13F · holdings as of the latest quarter funds have reported
RA CAPITAL MANAGEMENT, L.P.
9,905,045.0 sh
$435.7M
TPG GP A, LLC
6,494,962.0 sh
$285.7M
VIKING GLOBAL INVESTORS LP
3,195,181.0 sh
$140.6M
Atlas Venture Life Science Advisors, LLC
2,995,602.0 sh
$131.8M
ORBIMED ADVISORS LLC
2,555,877.0 sh
$112.4M
SCHEDULE 13D/G
No 5%+ ownership filings
Nobody has crossed 5% with a filing obligation. Absence is a fact here, not missing data.
Planned sales · Form 144
Filed before the sale — intent, not a trade
JENNIFER FITZPATRICK
FILED 2026-07-06
$450.9K
Fund concentration
N-PORT · funds ranked by how much of THEMSELVES they put in this stock — the conviction number 13F cannot show
PGIM Jennison Health Sciences Fund
$23.8M POSITION · AS OF 2026-02-27
1.6%
Eventide Healthcare & Life Sciences Fund
$25.8M POSITION · AS OF 2026-03-31
1.6%
ALPS Medical Breakthroughs ETF
$1.5M POSITION · AS OF 2026-02-28
1.1%
JPMorgan Small Cap Growth Fund
$22.1M POSITION · AS OF 2026-03-31
1.0%
Virtus Biotech Clinical Trials Etf
$249.7K POSITION · AS OF 2026-04-30
0.7%
JPMorgan Small Cap Blend Fund
$7.1M POSITION · AS OF 2026-03-31
0.5%
SEC N-PORT, MONTHLY WITH A ~60-DAY PUBLIC LAG · FUNDS ≥ $10M · % = SHARE OF THE FUND'S OWN BOOK
Clinical pipeline
ClinicalTrials.gov · 2 registered trials, 2 still enrolling or running — a status change here is dated weeks before the press release
1
Phase 1
1 ACTIVE
1
Phase 2
1 ACTIVE
TRIALS MATCHED TO THIS TICKER BY SPONSOR NAME · STUDIES RUN UNDER A SUBSIDIARY'S OWN NAME ARE NOT INCLUDED
Fundamentals
Annual figures from XBRL filings · pick a past date to see them exactly as the market knew them then — restatements and all
2025-122024-12
OPERATING INCOME$-89.0M$-70.6M
NET INCOME$-75.3M$-61.7M
EPS (DILUTED)-1.88-15.99
OPERATING CASH FLOW$-66.3M$-52.8M
CASH$58.5M$37.8M
SEC XBRL · FISCAL-YEAR PERIODS · AS KNOWN ON 2026-09-04 · NOBODY ELSE SHOWS FUNDAMENTALS AS OF A PAST DATE
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Public filings, honestly analyzed. Official US government sources in one desk — every figure carries the date it was filed, and the methodology is published, backtest included.

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© 2026 WAVEMAN · SOURCE: SEC EDGAR & OFFICIAL GOVERNMENT DATA · NOT INVESTMENT ADVICE · CHART BY TRADINGVIEW · UPDATED 2026-09-04 ALL SYSTEMS LIVE FOR MACHINES →