STOCK Act, US House only, disclosed up to 45 days after the trade
Funds added, last quarter
189
13F, latest reported quarter
Conversions, 180 days
11
Codes C/M, not in net · $10.9M priced
What the filings say about TWST
Insiders, 180 days
-$134.3M net sold
10 sellers · 40% of sales under a 10b5-1 plan
Planned sales (Form 144), 90 days
$118.0M
40 notices
Twist Bioscience insider trades (Form 4)
Form 4 buys and sells (codes P and S). Grants, option exercises
and conversions excluded.
Over the last 180 days, Twist Bioscience Corp insiders sold a net $134.3M of stock across 544 Form 4 purchases and sales, with no insider buying. Source: SEC Form 4 filings, as of 2026-10-27.
27 earlier Form 4 trades (code P or S) here by this insider (27 sales), the last on Oct 2, 2026.
The trade is 2.5% of the 98,114 shares held after it.
5 other insiders sold within 30 days.
189 funds added in the 13F quarter to Jun 30, 2026.
Insider activity: Chief Financial Officer Laponis Adam sold about $384.8K of TWST on Oct 9, 2026; 5 other insiders sold within 30 days and 189 funds added in the latest 13F quarter.
148 earlier Form 4 trades (code P or S) here by this insider (148 sales), the last on Oct 2, 2026.
The trade is 0.3% of the 565,468 shares held after it.
5 other insiders sold within 30 days.
189 funds added in the 13F quarter to Jun 30, 2026.
Insider activity: Chief Executive Officer Leproust Emily M. sold about $368.8K of TWST under a 10b5-1 plan on Oct 5, 2026; 5 other insiders sold within 30 days and 189 funds added in the latest 13F quarter.
148 earlier Form 4 trades (code P or S) here by this insider (148 sales), the last on Oct 2, 2026.
The trade is 0.1% of the 564,987 shares held after it.
5 other insiders sold within 30 days.
189 funds added in the 13F quarter to Jun 30, 2026.
Insider activity: Chief Executive Officer Leproust Emily M. sold about $96.8K of TWST under a 10b5-1 plan on Oct 5, 2026; 5 other insiders sold within 30 days and 189 funds added in the latest 13F quarter.
148 earlier Form 4 trades (code P or S) here by this insider (148 sales), the last on Oct 2, 2026.
The trade is 0.2% of the 563,970 shares held after it.
5 other insiders sold within 30 days.
189 funds added in the 13F quarter to Jun 30, 2026.
Insider activity: Chief Executive Officer Leproust Emily M. sold about $205.8K of TWST under a 10b5-1 plan on Oct 5, 2026; 5 other insiders sold within 30 days and 189 funds added in the latest 13F quarter.
148 earlier Form 4 trades (code P or S) here by this insider (148 sales), the last on Oct 2, 2026.
The trade is 0.1% of the 563,538 shares held after it.
5 other insiders sold within 30 days.
189 funds added in the 13F quarter to Jun 30, 2026.
Insider activity: Chief Executive Officer Leproust Emily M. sold about $88.0K of TWST under a 10b5-1 plan on Oct 5, 2026; 5 other insiders sold within 30 days and 189 funds added in the latest 13F quarter.
544 transactions on record
Since filing: total return from the first close after the filing to the latest close, dividend-adjusted. Not a forecast.
Context lines are counts over the filings above and returns from our own price history, never a price level. Not investment advice.
Nobody has filed for crossing 5%. That is a fact, not missing data.
TWST planned insider sales (Form 144)
Notice of intent to sell, filed before any sale
Finn Patrick John
Filed 2026-10-23
$302.2K
Laponis Adam
Filed 2026-10-09
$384.8K
Leproust Emily M.
Filed 2026-10-05
$919.4K
Cho Dennis
Filed 2026-10-02
$1.8M
Finn Patrick John
Filed 2026-10-02
$4.9M
TWST mutual fund holders (N-PORT)
Funds ranked by the share of their own portfolio in this stock (N-PORT).
ARK Genomic Revolution ETF
$120.4M position · as of 2026-07-31
7.7%
Artisan Small Cap Fund
$53.2M position · as of 2026-06-30
5.5%
iShares Genomics Immunology and Healthcare ETF
$9.1M position · as of 2026-07-31
4.8%
Alger Mid Cap 40 ETF
$7.4M position · as of 2026-06-30
4.8%
Global X Genomics & Biotechnology ETF
$2.2M position · as of 2026-05-31
4.0%
American Beacon ARK Transformational Innovation Fund
$6.3M position · as of 2026-06-30
4.0%
SEC N-PORT, monthly, about 60 days late · funds ≥ $10M ·
% is the share of the fund's own portfolio
Executive pay vs shareholder return · Dr.
CEO pay, headline and as actually paid, against the company's
return and its chosen peers' (DEF 14A).
FY
CEO total
Actually paid
Other execs, avg
TSR
Peer TSR
2025
$13.8M
$928.1K
$4.8M
-63%
+19%
2024
$7.6M
$25.0M
$2.7M
-41%
+16%
2023
$8.0M
$3.2M
$3.1M
-73%
-5%
2022
$5.9M
-$15.0M
$2.5M
-54%
-10%
2021
$1.3M
$18.1M
$728.1K
+41%
+20%
Tagged by the company under SEC Item 402(v). Returns are
cumulative from the start of the disclosure period. Green where the company beat its own peer group.
Live price
Daily candles from TradingView, under their licence. No filings marked.
Why this name is on the desk
Insiders have filed to sell, before selling.
The record shows a net $134.3M sold by insiders over 180 days, 189 funds added last quarter, $118.0M in planned Form 144 sales. Each figure is a federal filing, dated the day it went public.
Ratios from the company's XBRL filings, latest filings
Revenue, TTM
$431.8M
four quarters, 2025-07-01 to 2026-06-30
Revenue, TTM TWST
FY Sep 2025
$376.6M
FY Sep 2024
$313.0M
FY Sep 2023
$245.1M
FY Sep 2022
$203.6M
FY Sep 2021
$132.3M
Jun 2026
$118.4M
Mar 2026
$110.7M
Dec 2025
$103.7M
Sep 2025
$99.0M
Jun 2025
$96.1M
Mar 2025
$92.8M
Dec 2024
$88.7M
Sep 2024
$84.7M
At each fiscal year end
Single quarter
Net margin, TTM
-31.7%
net income over revenue, 2025-07-01 to 2026-06-30
Net margin, TTM TWST
FY Sep 2025
-20.6%
FY Sep 2024
-66.7%
FY Sep 2023
-83.5%
FY Sep 2022
-107.0%
FY Sep 2021
-114.9%
Jun 2026
-29.6%
Mar 2026
-39.8%
Dec 2025
-29.4%
Sep 2025
-27.4%
Jun 2025
+21.2%
Mar 2025
-42.4%
Dec 2024
-35.6%
Sep 2024
-40.9%
At each fiscal year end
Single quarter
Free cash flow, TTM
-$93.1M
operating cash flow minus capex, 2025-07-01 to 2026-06-30
Free cash flow, TTM TWST
FY Sep 2025
-$75.6M
FY Sep 2024
-$69.2M
FY Sep 2023
-$170.3M
FY Sep 2022
-$226.2M
FY Sep 2021
-$139.3M
Jun 2026
-$8.6M
Mar 2026
-$25.4M
Dec 2025
-$34.8M
Sep 2025
-$24.2M
Jun 2025
-$10.6M
Mar 2025
-$17.1M
Dec 2024
-$23.7M
Sep 2024
-$17.3M
At each fiscal year end
Single quarter
Debt to equity
0.00x
long-term 2020-12-31 (66 months older than the period end) plus current 2022-09-30 (45 months older than the period end); equity 2026-06-30
Debt to equity TWST
FY Sep 2025
0.00x
FY Sep 2024
0.00x
FY Sep 2023
0.00x
FY Sep 2022
0.00x
FY Sep 2021
0.00x
Jun 2026
0.00x
Mar 2026
0.00x
Dec 2025
0.00x
Sep 2025
0.00x
Jun 2025
0.00x
Mar 2025
0.00x
Dec 2024
0.00x
Sep 2024
0.00x
At each fiscal year end
Trailing four quarters at each quarter end
Cash flow to debt
-84.92x
TTM operating cash flow over long-term 2020-12-31 (66 months older than the period end) plus current 2022-09-30 (45 months older than the period end)
Cash flow to debt TWST
FY Sep 2025
-76.20x
FY Sep 2024
-102.55x
FY Sep 2023
-227.96x
FY Sep 2022
-199.02x
FY Sep 2021
-51.56x
Jun 2026
-84.92x
Mar 2026
-88.94x
Dec 2025
-81.62x
Sep 2025
-76.20x
Jun 2025
-81.81x
Mar 2025
-89.78x
Dec 2024
-100.08x
Sep 2024
-102.55x
At each fiscal year end
Trailing four quarters at each quarter end
Return on equity
-29.6%
TTM net income over average of 2025-06-30 and 2026-06-30
Return on equity TWST
FY Sep 2025
-16.4%
FY Sep 2024
-38.1%
FY Sep 2023
-29.0%
FY Sep 2022
-31.8%
FY Sep 2021
-33.2%
Jun 2026
-29.6%
Mar 2026
-18.2%
Dec 2025
-16.8%
Sep 2025
-16.4%
Jun 2025
-17.6%
Mar 2025
-38.2%
Dec 2024
-37.7%
Sep 2024
-38.1%
At each fiscal year end
Trailing four quarters at each quarter end
Return on assets
-20.8%
TTM net income over average of 2025-06-30 and 2026-06-30
Return on assets TWST
FY Sep 2025
-12.4%
FY Sep 2024
-30.0%
FY Sep 2023
-23.5%
FY Sep 2022
-26.2%
FY Sep 2021
-27.6%
Jun 2026
-20.8%
Mar 2026
-12.8%
Dec 2025
-12.3%
Sep 2025
-12.4%
Jun 2025
-13.3%
Mar 2025
-29.4%
Dec 2024
-29.4%
Sep 2024
-30.0%
At each fiscal year end
Trailing four quarters at each quarter end
Return on invested capital
n/a
pre-tax loss, no effective tax rate to apply
Return on invested capital TWST
FY Sep 2025
n/a
FY Sep 2024
n/a
FY Sep 2023
n/a
FY Sep 2022
n/a
FY Sep 2021
n/a
Jun 2026
n/a
Mar 2026
n/a
Dec 2025
n/a
Sep 2025
n/a
Jun 2025
n/a
Mar 2025
n/a
Dec 2024
n/a
Sep 2024
n/a
At each fiscal year end
Trailing four quarters at each quarter end
Return on capital employed
-26.2%
operating income (EBIT proxy) over average of 2025-06-30 and 2026-06-30 minus current liabilities
Return on capital employed TWST
FY Sep 2025
-24.9%
FY Sep 2024
-35.4%
FY Sep 2023
-27.6%
FY Sep 2022
-31.1%
FY Sep 2021
-30.5%
Jun 2026
-26.2%
Mar 2026
-25.8%
Dec 2025
-24.5%
Sep 2025
-24.9%
Jun 2025
-25.4%
Mar 2025
-34.8%
Dec 2024
-34.6%
Sep 2024
-35.4%
At each fiscal year end
Trailing four quarters at each quarter end
P/E, trailing
n/a
trailing loss, a multiple of a loss is not meaningful
P/E, trailing TWST
FY Sep 2025
n/a
FY Sep 2024
n/a
FY Sep 2023
n/a
FY Sep 2022
n/a
FY Sep 2021
n/a
Jun 2026
n/a
Mar 2026
n/a
Dec 2025
n/a
Sep 2025
n/a
Jun 2025
n/a
Mar 2025
n/a
Dec 2024
n/a
Sep 2024
n/a
At each fiscal year end
Trailing four quarters at each quarter end
Enterprise value
$9.0B
market value at close 2026-10-26 on 2026-07-29 shares, plus long-term 2020-12-31 (66 months older than the period end) plus current 2022-09-30 (45 months older than the period end), minus cash 2026-06-30
Enterprise value TWST
FY Sep 2025
$1.5B
FY Sep 2024
$2.4B
FY Sep 2023
$877.0M
FY Sep 2022
$1.6B
FY Sep 2021
$4.8B
Jun 2026
$6.3B
Mar 2026
$2.8B
Dec 2025
$1.8B
Sep 2025
$1.5B
Jun 2025
$2.0B
Mar 2025
$2.1B
Dec 2024
$2.5B
Sep 2024
$2.4B
At each fiscal year end
Trailing four quarters at each quarter end
FCF yield
-1.0%
TTM free cash flow over market value at close 2026-10-26
FCF yield TWST
FY Sep 2025
-4.5%
FY Sep 2024
-2.6%
FY Sep 2023
-14.6%
FY Sep 2022
-11.4%
FY Sep 2021
-2.6%
Jun 2026
-1.5%
Mar 2026
-3.3%
Dec 2025
-4.5%
Sep 2025
-4.5%
Jun 2025
-3.1%
Mar 2025
-2.8%
Dec 2024
-2.5%
Sep 2024
-2.6%
At each fiscal year end
Trailing four quarters at each quarter end
PEG, trailing
n/a
trailing loss, a multiple of a loss is not meaningful
PEG, trailing TWST
FY Sep 2025
n/a
FY Sep 2024
n/a
FY Sep 2023
n/a
FY Sep 2022
n/a
FY Sep 2021
n/a
Jun 2026
n/a
Mar 2026
n/a
Dec 2025
n/a
Sep 2025
n/a
Jun 2025
n/a
Mar 2025
n/a
Dec 2024
n/a
Sep 2024
n/a
At each fiscal year end
Trailing four quarters at each quarter end
Price as of 2026-10-26. Hover or tap a tile for its yearly and quarterly history.Method
TTM is four consecutive fiscal quarters; Q4 is the year minus nine months when not filed. Returns use the average of opening and closing balances. EBIT is approximated by operating income. PEG uses trailing EPS growth.
Fundamentals
Annual figures from XBRL filings. Pick a past date to see them as known then.
TWST ranks highest on growth (78th percentile) and institutional and government (73rd), and lowest on insider conviction (2nd), among Pharma & Biotech peers.
Profitability
67
Inputs
Return on equity-29.6% · 67 pct, sector of 545
Return on assets-20.8% · 66 pct, sector of 691
Return on invested capitalpre-tax loss, no effective tax rate to apply
Return on capital employed-26.2% · 69 pct, sector of 576
Financial health
46
Inputs
Debt to equity0.00x · 84 pct, sector of 352
Cash flow to debt-84.92x · 8 pct, sector of 371
Growth
78
Inputs
Revenue growth, YoY+20.3% · 67 pct, sector of 505
Backlog growth, YoY+63.4% · 90 pct, sector of 40
Insider conviction
2
Inputs
Net Form 4 buying (codes P and S), 180d-$50.0M · 4 pct, sector of 428
Insider buyers, 180d0 · 0 pct, sector of 437
Institutional and government
73
Inputs
Funds adding, latest quarter189 · 88 pct, sector of 698
Congress net buyers, 365dno Congress trades in 365 days
Federal contracts, 180dno federal contracts in 180 days
Lobbying spend, 4 quarters$315K · 58 pct, sector of 133
Risk and compliance
27
Inputs
Short interest, % of float+17.1% · 21 pct, sector of 813
Recalls per $1B revenue, 3ynot measured for this sector, almost no peer has an event
EPA cases per $1B revenue, 5ynot measured for this sector, almost no peer has an event
New text in Risk Factors, latest 10-K+13.8% · 34 pct, sector of 511
1 not measured: US patents
US patents needs 1 of 2 inputs, 0 present: patent data not loaded yet
6 of 7 axes scored. Each is a percentile against sector peers (all companies when the sector is thin); higher is better. An unscored axis is unmeasured, not low. How it is scored
TWST filings, in plain words
Are Twist Bioscience insiders buying or selling TWST?
In the 180 days to 2026-10-27, Twist Bioscience insiders were net sellers, a net $134.3M across purchases and sales reported on Form 4, by 10 sellers.
Are there planned insider sales of TWST?
Yes. 40 Form 144 notices of planned insider sales were filed in the 90 days to 2026-10-27, covering $118.0M of stock; the latest, by Finn Patrick John, was filed 2026-10-23.
Read the full summary
In the 180 days to 2026-10-27, Twist Bioscience insiders were net sellers of TWST, a net $134.3M across purchases and sales reported on Form 4 by 10 sellers. 40% of the 115 insider sales were made under a Rule 10b5-1 plan; the rest were not flagged as planned. Insiders filed 40 Form 144 notices of intent to sell in the 90 days to 2026-10-27, covering $118.0M of stock. Each figure is counted from SEC and House filings as of 2026-10-27, dated the day the filing was made public.
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