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RYTM · Rhythm Pharmaceuticals, Inc.
> Ask across nine datasets ⌘K
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TEAM-0.32% 13F +439META+2.47% 13F +2,694RCG-2.04% CLUSTERUTHR-4.03% 13F +425CRWV+4.49% 13F +693CRM+2.92% 13F +1,018CVNA-0.98% 13F +794TPL-0.71% 13F +444NET-4.47% 13F +710MSTR-1.35% 13F +526DELL+4.91% 13F +1,203CRWD+5.68% 13F +1,382ANET+1.22% 13F +1,323COIN+10.14% 13F +475TEAM-0.32% 13F +439META+2.47% 13F +2,694RCG-2.04% CLUSTERUTHR-4.03% 13F +425CRWV+4.49% 13F +693CRM+2.92% 13F +1,018CVNA-0.98% 13F +794TPL-0.71% 13F +444NET-4.47% 13F +710MSTR-1.35% 13F +526DELL+4.91% 13F +1,203CRWD+5.68% 13F +1,382ANET+1.22% 13F +1,323COIN+10.14% 13F +475
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RYTM

RHYTHM PHARMACEUTICALS, INC.
PHARMA & BIOTECH · PHARMACEUTICAL PREPARATIONS · CIK 0001649904
FORM 144 · 8☆ WATCH
INSIDER NET · 180D
-$27.8M
open-market buys minus sells, Form 4 codes P and S
INSIDER BUYERS · 180D
0
CONGRESS BUYERS · 1Y
0
FUNDS ADDED · QTR
172
13F, latest reported quarter
REVENUE GROWTH
+45.8%
XBRL, annual
NET MARGIN
-103.6%
CONVERSIONS · 180D
17
codes C/M, not in net · $4.1M priced
SEVEN FACTS, RANKED AGAINST THE SECTOR · RANK IS NOT A FORECAST
INSIDERS
net -$27.8M over 180 days
-$27.4M over 90 days
below 91% of Pharma & Biotech
CONGRESS
no member of Congress has reported trading it
FUNDS
172 funds added or opened last quarter
more than 83% of Pharma & Biotech
REVENUE
+45.8% year over year
more than 77% of Pharma & Biotech
MARGIN
-103.6% net margin
below 66% of Pharma & Biotech
BUYBACKS
no share repurchases reported
SHORT
no short interest reported
THE SITUATION · EVERY LINE IS ONE RULE OVER ONE DATASET
Insiders are net sellers: -$27.8M across 7 people in 180 days.
172 funds added or opened positions in the latest 13F quarter, of 307 holders.
The year, with the filings on it
Total return indexed to 100 over the last 12 months · every marker is a federal filing, placed at its date — hover any marker for the detail
TOTAL 12M RETURN +1.2%
+1.2%12M
-27%-14%-1%+13%2025-092025-102025-122026-032026-052026-072026-09 2026-08-13 · Lee Jennifer Kayden sold $8.9M2026-06-22 · TETRAULT LYNN A. sold $3.7M2026-08-31 · Smith Hunter C sold $3.0M2026-08-31 · Smith Hunter C sold $2.4M2026-08-12 · Mazabraud Yann sold $2.1M2026-08-12 · Mazabraud Yann sold $2.0M2025-11-07 · Cramer Pamela J. sold $1.9M2025-09-02 · Shulman Joseph sold $1.8M2026-08-12 · Mazabraud Yann sold $1.7M2026-08-31 · Smith Hunter C sold $1.2M2025-10-30 · Shulman Joseph sold $1.1M2025-10-16 · Shulman Joseph sold $933.7K2026-08-13 · Shulman Joseph sold $608.2K2026-03-04 · German Christopher Paul sold $502.8K2026-05-15 · German Christopher Paul sold $428.1K2026-08-12 · Mazabraud Yann sold $413.5K2026-08-13 · Garfield Alastair sold $402.2K2025-10-16 · Shulman Joseph sold $384.9K2025-12-11 · Cramer Pamela J. sold $371.9K2026-02-05 · Smith Hunter C sold $358.6K2025-11-20 · Cramer Pamela J. sold $351.8K2025-11-10 · Cramer Pamela J. sold $351.5K2025-10-28 · Shulman Joseph sold $323.8K2025-10-16 · Shulman Joseph sold $298.8K2026-08-12 · Mazabraud Yann sold $257.1K2026-08-13 · Garfield Alastair sold $233.0K2026-02-11 · Smith Hunter C sold $222.9K2026-02-10 · Smith Hunter C sold $196.4K2026-08-13 · Garfield Alastair sold $182.2K2026-02-19 · Smith Hunter C sold $170.8K2026-02-04 · Smith Hunter C sold $157.1K2026-02-19 · Smith Hunter C sold $131.2K2026-02-17 · Smith Hunter C sold $119.3K2026-08-12 · Mazabraud Yann sold $112.9K2026-02-17 · Smith Hunter C sold $110.1K2026-02-04 · Smith Hunter C sold $106.6K2026-08-13 · Garfield Alastair sold $95.3K2026-02-17 · Smith Hunter C sold $91.5K2026-02-19 · Smith Hunter C sold $81.7K2026-02-04 · Smith Hunter C sold $80.4K2026-02-12 · Smith Hunter C sold $79.2K2026-02-10 · Smith Hunter C sold $72.6K2026-08-31 · HUNTER SMITH filed to sell $6.7M2026-08-13 · ALASTAIR GARFIELD filed to sell $912.9K2026-08-13 · Jennifer Kayden Lee filed to sell $8.9M2026-08-13 · JOSEPH J SHULMAN filed to sell $597.3K2026-08-12 · YANN MAZABRAUD filed to sell $6.4M2026-08-11 · PAMELA CRAMER filed to sell $1.3M2026-08-10 · PAMELA CRAMER filed to sell $407.0K2026-06-22 · LYNN TETRAULT filed to sell $3.6M
INSIDER SELLFORM 144
INDEXED RETURN, DIVIDEND-ADJUSTED — NOT A PRICE CHART · LARGE TRADES DRAWN FIRST WHEN A NAME FILES HEAVILY
Live price
Daily candles from TradingView, on their licence — no filings are marked on this one
WHY THIS NAME IS ON THE DESK
Insiders have filed to sell — before selling.
The record shows a net $27.8M sold by insiders over 180 days, 172 funds added last quarter, $28.9M in planned Form 144 sales. Every figure is a federal filing, dated the day it became public.
Same sector, ranked by filing activity
Sector from the SEC's own SIC classification
Insider transactions
Form 4 purchases and sales (codes P and S) — grants, option exercises and preferred conversions excluded

Over the last 180 days, RHYTHM PHARMACEUTICALS, INC. insiders sold a net $27.8M of stock across 220 Form 4 purchases and sales, with 0 insider(s) buying. Source: SEC Form 4 filings, as of 2026-09-05.

INSIDER
FILED
SHARES
VALUE
Smith Hunter C
Chief Financial Officer
SELL
2026-08-31
23,072.0
$2.4M
Smith Hunter C
Chief Financial Officer
SELL
2026-08-31
11,514.0
$1.2M
Smith Hunter C
Chief Financial Officer
SELL
2026-08-31
28,188.0
$3.0M
Lee Jennifer Kayden
EVP, Head of North America
SELL
2026-08-13
75,834.0
$8.9M
Garfield Alastair
Chief Scientific Officer
SELL
2026-08-13
2,007.0
$233.0K
220 TRANSACTIONS ON RECORD

Showing the most recent few. Create a free account to see 215 more transactions on record, the cross-source screener and CSV export. We store only your email address, and there is no password to create.

Institutional holders
13F · holdings as of the latest quarter funds have reported
RA CAPITAL MANAGEMENT, L.P.
6,666,837.0 sh
$740.2M
BlackRock, Inc.
6,156,902.0 sh
$683.6M
BAKER BROS. ADVISORS LP
5,604,483.0 sh
$622.3M
PRIMECAP MANAGEMENT CO/CA/
3,168,853.0 sh
$351.8M
VANGUARD PORTFOLIO MANAGEMENT LLC
3,136,895.0 sh
$348.3M
SCHEDULE 13D/G
No 5%+ ownership filings
Nobody has crossed 5% with a filing obligation. Absence is a fact here, not missing data.
Planned sales · Form 144
Filed before the sale — intent, not a trade
HUNTER SMITH
FILED 2026-08-31
$6.7M
ALASTAIR GARFIELD
FILED 2026-08-13
$912.9K
Jennifer Kayden Lee
FILED 2026-08-13
$8.9M
JOSEPH J SHULMAN
FILED 2026-08-13
$597.3K
YANN MAZABRAUD
FILED 2026-08-12
$6.4M
Fund concentration
N-PORT · funds ranked by how much of THEMSELVES they put in this stock — the conviction number 13F cannot show
Harbor Health Care ETF
$1.0M POSITION · AS OF 2026-04-30
3.8%
PRIMECAP Odyssey Aggressive Growth Fund
$172.8M POSITION · AS OF 2026-04-30
2.5%
AlphaCentric Life Sciences and Healthcare Fund
$808.6K POSITION · AS OF 2026-03-31
2.1%
Federated Hermes Kaufmann Small Cap Fund
$48.2M POSITION · AS OF 2026-04-30
1.7%
PRIMECAP Odyssey Growth Fund
$89.1M POSITION · AS OF 2026-04-30
1.6%
Harbor Human Capital Factor US Small Cap ETF
$2.5M POSITION · AS OF 2026-04-30
1.6%
SEC N-PORT, MONTHLY WITH A ~60-DAY PUBLIC LAG · FUNDS ≥ $10M · % = SHARE OF THE FUND'S OWN BOOK
Clinical pipeline
ClinicalTrials.gov · 21 registered trials, 5 still enrolling or running — a status change here is dated weeks before the press release
8
Phase 2
2 ACTIVE
9
Phase 3
2 ACTIVE
1
Phase 4
0 ACTIVE
3
Multi-phase
1 ACTIVE
TRIALS MATCHED TO THIS TICKER BY SPONSOR NAME · STUDIES RUN UNDER A SUBSIDIARY'S OWN NAME ARE NOT INCLUDED
Executive pay vs shareholder return · David P. Meeker
DEF 14A pay-versus-performance disclosure · both the headline pay and the SEC's mark-to-market figure, beside the return the company delivered and the return of the peer group it chose itself
FY
CEO TOTAL
ACTUALLY PAID
OTHER NEOs AVG
TSR
PEER TSR
2025
$17.5M
$54.2M
$5.6M
+260%
-6%
2024
$14.7M
$18.7M
$4.6M
+88%
-7%
2023
$7.2M
$19.0M
$2.0M
+55%
-6%
2022
$3.3M
$24.1M
$1.1M
-2%
-10%
2021
$6.5M
-$10.0M
$2.1M
-66%
+0%
TAGGED BY THE COMPANY UNDER SEC ITEM 402(v) · RETURN IS CUMULATIVE FROM THE START OF THE DISCLOSURE PERIOD · GREEN WHERE THE COMPANY BEAT ITS OWN PEER GROUP
Fundamentals
Annual figures from XBRL filings · pick a past date to see them exactly as the market knew them then — restatements and all
2025-122024-122023-122022-12
REVENUE$189.8M$130.1M$77.4M$23.6M
OPERATING INCOME$-192.0M$-265.5M$-184.4M$-179.2M
NET INCOME$-196.5K$-260.6K$-184.7K$-181.1K
EPS (DILUTED)-3.11-4.34-3.20-3.47
OPERATING CASH FLOW$-115.7M$-113.9M$-136.2M$-173.4M
CASH$54.3M$89.1M$60.1M$127.7M
LONG-TERM DEBT$100.9M$108.3M$106.1M
SEC XBRL · FISCAL-YEAR PERIODS · AS KNOWN ON 2026-09-05 · NOBODY ELSE SHOWS FUNDAMENTALS AS OF A PAST DATE
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Public filings, honestly analyzed. Official US government sources in one desk — every figure carries the date it was filed, and the methodology is published, backtest included.

SEC FORM 4FORM 13F 13D/GFORM 144XBRL STOCK ACTCONTRACTSFEC CFPBNRC
© 2026 WAVEMAN · SOURCE: SEC EDGAR & OFFICIAL GOVERNMENT DATA · NOT INVESTMENT ADVICE · CHART BY TRADINGVIEW · UPDATED 2026-09-05 ALL SYSTEMS LIVE FOR MACHINES →