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WAVEMAN · COMPANY
PRAX · Praxis Precision Medicines, Inc.
> Ask across nine datasets ⌘K
LIVE
TEAM-2.62% 13F +440META+1.00% 13F +2,694RCG+0.35% CLUSTERUTHR-0.54% 13F +425CRWV+5.68% 13F +694CRM-1.97% 13F +1,019CVNA+1.58% 13F +795TPL-1.11% 13F +444NET-1.96% 13F +711MSTR-1.39% 13F +527DELL+1.50% 13F +1,204CRWD-0.87% 13F +1,383ANET+1.22% 13F +1,324COIN-4.18% 13F +475TEAM-2.62% 13F +440META+1.00% 13F +2,694RCG+0.35% CLUSTERUTHR-0.54% 13F +425CRWV+5.68% 13F +694CRM-1.97% 13F +1,019CVNA+1.58% 13F +795TPL-1.11% 13F +444NET-1.96% 13F +711MSTR-1.39% 13F +527DELL+1.50% 13F +1,204CRWD-0.87% 13F +1,383ANET+1.22% 13F +1,324COIN-4.18% 13F +475
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PRAX

Praxis Precision Medicines, Inc.
PHARMA & BIOTECH · PHARMACEUTICAL PREPARATIONS · CIK 0001689548
FORM 144 · 1☆ WATCH
INSIDER NET · 180D
-$3.6M
open-market buys minus sells, Form 4 codes P and S
INSIDER BUYERS · 180D
0
CONGRESS BUYERS · 1Y
0
FUNDS ADDED · QTR
183
13F, latest reported quarter
REVENUE GROWTH
-100.0%
XBRL, annual
NET MARGIN
-
CONVERSIONS · 180D
2
codes C/M, not in net · $826.0K priced
SEVEN FACTS, RANKED AGAINST THE SECTOR · RANK IS NOT A FORECAST
INSIDERS
net -$3.6M over 180 days
-$3.6M over 90 days
below 75% of Pharma & Biotech
CONGRESS
no member of Congress has reported trading it
FUNDS
183 funds added or opened last quarter
more than 85% of Pharma & Biotech
REVENUE
-100.0% year over year
the lowest in Pharma & Biotech
MARGIN
no margin: this company reports no revenue to divide by
BUYBACKS
no share repurchases reported
SHORT
no short interest reported
THE SITUATION · EVERY LINE IS ONE RULE OVER ONE DATASET
183 funds added or opened positions in the latest 13F quarter, of 313 holders.
The year, with the filings on it
Total return indexed to 100 over the last 12 months · every marker is a federal filing, placed at its date — hover any marker for the detail
TOTAL 12M RETURN +682.8%
+682.8%12M
-16%+242%+501%+760%2025-092025-102025-122026-032026-052026-072026-09 2025-10-16 · Gross Phillip sold $26.1M2025-10-16 · Gross Phillip sold $2.8M2025-10-16 · Gross Phillip sold $2.7M2025-11-20 · Nemiroff Alex sold $2.6M2025-11-20 · Mastrocola Lauren sold $2.2M2025-11-20 · Nemiroff Alex sold $1.8M2025-10-16 · Gross Phillip sold $1.1M2026-06-24 · DeSimone Jill sold $890.2K2026-06-24 · DeSimone Jill sold $544.1K2025-11-20 · Mastrocola Lauren sold $413.4K2026-06-24 · DeSimone Jill sold $402.8K2026-06-24 · DeSimone Jill sold $382.2K2025-11-20 · Nemiroff Alex sold $327.1K2026-06-24 · DeSimone Jill sold $314.1K2026-06-24 · DeSimone Jill sold $309.1K2026-06-24 · DeSimone Jill sold $264.2K2025-10-16 · Gross Phillip sold $216.1K2026-06-24 · DeSimone Jill sold $209.5K2025-11-20 · Nemiroff Alex sold $188.8K2026-06-24 · DeSimone Jill sold $158.1K2025-10-16 · Gross Phillip sold $125.4K2026-06-24 · DeSimone Jill sold $97.7K2025-10-16 · Gross Phillip sold $64.1K2025-10-16 · Gross Phillip sold $56.0K2025-10-16 · Gross Phillip sold $40.7K2025-10-16 · Gross Phillip sold $40.7K2026-06-24 · DeSimone Jill sold $36.4K2026-06-24 · DeSimone Jill sold $3.0K2026-06-24 · DeSimone Jill filed to sell $3.6M
INSIDER SELLFORM 144
INDEXED RETURN, DIVIDEND-ADJUSTED — NOT A PRICE CHART · LARGE TRADES DRAWN FIRST WHEN A NAME FILES HEAVILY
Live price
Daily candles from TradingView, on their licence — no filings are marked on this one
WHY THIS NAME IS ON THE DESK
Insiders have filed to sell — before selling.
The record shows a net $3.6M sold by insiders over 180 days, 183 funds added last quarter, $3.6M in planned Form 144 sales. Every figure is a federal filing, dated the day it became public.
Backtest this pattern Open the screener
Same sector, ranked by filing activity
Sector from the SEC's own SIC classification
UTHRCPIXMRNAREGNLLYALNYELFCITRMDGLDNAVRTXNUVL
Insider transactions
Form 4 purchases and sales (codes P and S) — grants, option exercises and preferred conversions excluded

Over the last 180 days, Praxis Precision Medicines, Inc. insiders sold a net $3.6M of stock across 55 Form 4 purchases and sales, with 0 insider(s) buying. Source: SEC Form 4 filings, as of 2026-09-06.

INSIDER
FILED
SHARES
VALUE
DeSimone Jill
Director
SELL
2026-06-24
10.0
$3.0K
DeSimone Jill
Director
SELL
2026-06-24
1,279.0
$402.8K
DeSimone Jill
Director
SELL
2026-06-24
837.0
$264.2K
DeSimone Jill
Director
SELL
2026-06-24
504.0
$158.1K
DeSimone Jill
Director
SELL
2026-06-24
1,004.0
$314.1K
55 TRANSACTIONS ON RECORD

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Institutional holders
13F · holdings as of the latest quarter funds have reported
Jupiter Topco LLC
3,421,374.0 sh
$1.1B
FMR LLC
2,316,907.0 sh
$775.7M
BlackRock, Inc.
2,292,585.0 sh
$767.5M
PERCEPTIVE ADVISORS LLC
2,035,986.0 sh
$681.6M
BAKER BROS. ADVISORS LP
1,753,198.0 sh
$587.0M
SCHEDULE 13D/G
No 5%+ ownership filings
Nobody has crossed 5% with a filing obligation. Absence is a fact here, not missing data.
Planned sales · Form 144
Filed before the sale — intent, not a trade
DeSimone Jill
FILED 2026-06-24
$3.6M
Fund concentration
N-PORT · funds ranked by how much of THEMSELVES they put in this stock — the conviction number 13F cannot show
Global X Genomics & Biotechnology ETF
$3.3M POSITION · AS OF 2026-02-28
6.2%
Invesco Dorsey Wright Healthcare Momentum ETF
$6.1M POSITION · AS OF 2026-04-30
5.1%
Driehaus Micro Cap Growth Fund
$11.9M POSITION · AS OF 2026-03-31
2.6%
Franklin Biotechnology Discovery Fund
$26.0M POSITION · AS OF 2026-04-30
2.5%
Select Biotechnology Portfolio
$131.5M POSITION · AS OF 2026-02-28
2.5%
Janus Henderson Global Life Sciences Fund
$127.3M POSITION · AS OF 2026-03-31
2.4%
SEC N-PORT, MONTHLY WITH A ~60-DAY PUBLIC LAG · FUNDS ≥ $10M · % = SHARE OF THE FUND'S OWN BOOK
Clinical pipeline
ClinicalTrials.gov · 13 registered trials, 8 still enrolling or running — a status change here is dated weeks before the press release
1
Phase 1
0 ACTIVE
3
Phase 2
1 ACTIVE
5
Phase 3
5 ACTIVE
1
Not applicable
0 ACTIVE
3
Multi-phase
2 ACTIVE
TRIALS MATCHED TO THIS TICKER BY SPONSOR NAME · STUDIES RUN UNDER A SUBSIDIARY'S OWN NAME ARE NOT INCLUDED
Executive pay vs shareholder return · Marcio Souza
DEF 14A pay-versus-performance disclosure · both the headline pay and the SEC's mark-to-market figure, beside the return the company delivered and the return of the peer group it chose itself
FY
CEO TOTAL
ACTUALLY PAID
OTHER NEOs AVG
TSR
PEER TSR
2025
$8.7M
$55.5M
$3.0M
-64%
+25%
2024
$13.4M
$20.6M
$4.0M
-91%
-7%
2023
$2.1M
$1.4M
$933.5K
-97%
-6%
2022
$6.0M
-$17.6M
$2.5M
-96%
-10%
2021
$10.9M
-$62.2M
$4.1M
-64%
+0%
TAGGED BY THE COMPANY UNDER SEC ITEM 402(v) · RETURN IS CUMULATIVE FROM THE START OF THE DISCLOSURE PERIOD · GREEN WHERE THE COMPANY BEAT ITS OWN PEER GROUP
Fundamentals
Annual figures from XBRL filings · pick a past date to see them exactly as the market knew them then — restatements and all
2025-122024-122023-122022-12
REVENUE$0$8.6M$2.4M$0
OPERATING INCOME$-326.2M$-200.2M$-126.4M$-215.0M
NET INCOME$-303.0M$-183.0M$-123.0M$-214.0M
EPS (DILUTED)-13.48-10.21-18.69-69.65
OPERATING CASH FLOW$-249.1M$-131.8M$-111.1M$-185.0M
CASH$357.3M$215.4M$81.3M$61.6M
SEC XBRL · FISCAL-YEAR PERIODS · AS KNOWN ON 2026-09-06 · NOBODY ELSE SHOWS FUNDAMENTALS AS OF A PAST DATE
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Public filings, honestly analyzed. Official US government sources in one desk — every figure carries the date it was filed, and the methodology is published, backtest included.

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© 2026 WAVEMAN · SOURCE: SEC EDGAR & OFFICIAL GOVERNMENT DATA · NOT INVESTMENT ADVICE · CHART BY TRADINGVIEW · UPDATED 2026-09-06 ALL SYSTEMS LIVE FOR MACHINES →