First Form 4 purchase or sale (code P or S) here by this insider on our record.
The trade is 87.7% of the 11,407 shares held after it.
No other insider bought within 30 days.
13 funds added in the 13F quarter to Jun 30, 2026.
Insider activity: Director KAITIN KENNETH I bought about $5.5K of CRIS on Mar 31, 2026, the largest insider purchase at the company on our record; 13 funds added in the latest 13F quarter.
1 earlier Form 4 trade (code P or S) here by this insider (1 sale), the last on Jan 27, 2022.
The trade is 4.8% of the 64,877 shares held after it.
No other insider sold within 30 days.
13 funds added in the 13F quarter to Jun 30, 2026.
Insider activity: President & CEO Dentzer James E sold about $9.5K of CRIS on Jan 31, 2022, the largest insider sale at the company on our record; 13 funds added in the latest 13F quarter.
First Form 4 purchase or sale (code P or S) here by this insider on our record.
The trade is 3.5% of the 67,971 shares held after it.
No other insider sold within 30 days.
13 funds added in the 13F quarter to Jun 30, 2026.
Insider activity: President & CEO Dentzer James E sold about $7.7K of CRIS on Jan 27, 2022, the largest insider sale at the company on our record; 13 funds added in the latest 13F quarter.
3 transactions on record · a thin record, read with care
Since filing: total return from the first close after the filing to the latest close, dividend-adjusted. Not a forecast.
Context lines are counts over the filings above and returns from our own price history, never a price level. Not investment advice.
Nobody has filed for crossing 5%. That is a fact, not missing data.
CRIS planned insider sales (Form 144)
No planned-sale notices
No insider has filed to sell. Watch this after a run-up.
CRIS mutual fund holders (N-PORT)
Funds ranked by the share of their own portfolio in this stock (N-PORT).
Fidelity Extended Market Index Fund
$66.1K position · as of 2026-05-31
0.0%
VANGUARD EXTENDED MARKET INDEX FUND
$50.1K position · as of 2026-06-30
0.0%
Fidelity Series Total Market Index Fund
$10.0K position · as of 2026-05-31
0.0%
Fidelity Nasdaq Composite Index Fund
$1.6K position · as of 2026-05-31
0.0%
VANGUARD TOTAL STOCK MARKET INDEX FUND
$112.6K position · as of 2026-06-30
0.0%
Fidelity Total Market Index Fund
$5.8K position · as of 2026-05-31
0.0%
SEC N-PORT, monthly, about 60 days late · funds ≥ $10M ·
% is the share of the fund's own portfolio
Clinical pipeline
4 registered trials, 2 still running (ClinicalTrials.gov).
A status change is dated here weeks before the press release.
1
Phase 1
0 active
1
Phase 2
1 active
2
Multi-phase
1 active
What changed recently
CA-4948-101: Open-Label, Dose Escalation and Expansion Trial of Emavusertib (CA-4948) in
2026-10-07 · Completion moved 2026-08 → 2027-07
PHASE1,PHASE2
Matched by sponsor name. Trials run under a subsidiary's
own name are not included.
Executive pay vs shareholder return · James E. Dentzer
CEO pay, headline and as actually paid, against the company's
return and its chosen peers' (DEF 14A).
FY
CEO total
Actually paid
Other execs, avg
TSR
Peer TSR
2025
$1.7M
$970.8K
$928.8K
-91%
n/a
2024
$2.0M
$860.6K
$1.1M
-72%
n/a
2023
$1.7M
$2.4M
$948.0K
+16%
n/a
2022
$3.0M
$2.3M
$1.1M
-7%
n/a
Tagged by the company under SEC Item 402(v). Returns are
cumulative from the start of the disclosure period. Green where the company beat its own peer group.
Live price
Daily candles from TradingView, under their licence. No filings marked.
Why this name is on the desk
The complete filing record, in one place.
The record shows 13 funds added last quarter. Each figure is a federal filing, dated the day it went public.
Ratios from the company's XBRL filings, latest filings
Revenue, TTM
$4.3M
four quarters, 2025-07-01 to 2026-06-30
Revenue, TTM CRIS
FY Dec 2025
$9.4M
FY Dec 2024
$10.9M
FY Dec 2023
$10.0M
FY Dec 2022
$10.2M
FY Dec 2021
$10.6M
Jun 2026
$0
Mar 2026
$0
Dec 2025
$1.1M
Sep 2025
$3.2M
Jun 2025
$2.7M
Mar 2025
$2.4M
Dec 2024
$3.3M
Sep 2024
$2.9M
At each fiscal year end
Single quarter
Net margin, TTM
-490.3%
net income over revenue, 2025-07-01 to 2026-06-30
Net margin, TTM CRIS
FY Dec 2025
-80.3%
FY Dec 2024
-397.8%
FY Dec 2023
-473.0%
FY Dec 2022
-557.7%
FY Dec 2021
-426.7%
Jun 2026
n/a
Mar 2026
n/a
Dec 2025
+1,701%
Sep 2025
-243.4%
Jun 2025
-312.6%
Mar 2025
-446.1%
Dec 2024
-287.5%
Sep 2024
-344.3%
At each fiscal year end
Single quarter
Free cash flow, TTM
-$30.6M
operating cash flow minus capex, 2025-07-01 to 2026-06-30
Free cash flow, TTM CRIS
FY Dec 2025
-$27.2M
FY Dec 2024
-$39.6M
FY Dec 2023
-$38.4M
FY Dec 2022
-$54.8M
FY Dec 2021
-$37.6M
Jun 2026
n/a
Mar 2026
n/a
Dec 2025
n/a
Sep 2025
n/a
Jun 2025
n/a
Mar 2025
n/a
Dec 2024
n/a
Sep 2024
n/a
At each fiscal year end
Single quarter
Debt to equity
0.00x
long-term 2021-09-30 (57 months older than the period end) plus current 2025-12-31 (6 months older than the period end); equity 2026-06-30
Debt to equity CRIS
FY Dec 2025
0.00x
FY Dec 2024
n/a
FY Dec 2023
0.43x
FY Dec 2022
0.00x
FY Dec 2021
0.00x
Jun 2026
0.00x
Mar 2026
0.00x
Dec 2025
0.00x
Sep 2025
n/a
Jun 2025
n/a
Mar 2025
n/a
Dec 2024
n/a
Sep 2024
n/a
At each fiscal year end
Trailing four quarters at each quarter end
Cash flow to debt
n/a
no debt to cover
Cash flow to debt CRIS
FY Dec 2025
n/a
FY Dec 2024
-5.24x
FY Dec 2023
-4.52x
FY Dec 2022
n/a
FY Dec 2021
n/a
Jun 2026
n/a
Mar 2026
n/a
Dec 2025
n/a
Sep 2025
-4.33x
Jun 2025
-4.14x
Mar 2025
-4.64x
Dec 2024
-5.24x
Sep 2024
-4.76x
At each fiscal year end
Trailing four quarters at each quarter end
Return on equity
n/a
average equity is zero or negative
Return on equity CRIS
FY Dec 2025
n/a
FY Dec 2024
-634.7%
FY Dec 2023
-143.2%
FY Dec 2022
-82.6%
FY Dec 2021
-41.0%
Jun 2026
n/a
Mar 2026
-693.9%
Dec 2025
n/a
Sep 2025
n/a
Jun 2025
n/a
Mar 2025
-2,951%
Dec 2024
-634.7%
Sep 2024
-436.2%
At each fiscal year end
Trailing four quarters at each quarter end
Return on assets
-87.8%
TTM net income over average of 2025-06-30 and 2026-06-30
Return on assets CRIS
FY Dec 2025
-24.8%
FY Dec 2024
-73.2%
FY Dec 2023
-50.9%
FY Dec 2022
-41.8%
FY Dec 2021
-24.8%
Jun 2026
-87.8%
Mar 2026
-61.3%
Dec 2025
-24.8%
Sep 2025
-104.3%
Jun 2025
-97.7%
Mar 2025
-83.1%
Dec 2024
-73.2%
Sep 2024
-68.7%
At each fiscal year end
Trailing four quarters at each quarter end
Return on invested capital
n/a
tax provision or pre-tax income not filed for the four quarters
Return on invested capital CRIS
FY Dec 2025
n/a
FY Dec 2024
n/a
FY Dec 2023
n/a
FY Dec 2022
n/a
FY Dec 2021
n/a
Jun 2026
n/a
Mar 2026
n/a
Dec 2025
n/a
Sep 2025
n/a
Jun 2025
n/a
Mar 2025
n/a
Dec 2024
n/a
Sep 2024
n/a
At each fiscal year end
Trailing four quarters at each quarter end
Return on capital employed
-115.6%
operating income (EBIT proxy) over average of 2025-06-30 and 2026-06-30 minus current liabilities
Return on capital employed CRIS
FY Dec 2025
-40.6%
FY Dec 2024
-114.9%
FY Dec 2023
-62.7%
FY Dec 2022
-42.8%
FY Dec 2021
-24.5%
Jun 2026
-115.6%
Mar 2026
-41.7%
Dec 2025
-40.6%
Sep 2025
-243.7%
Jun 2025
-185.6%
Mar 2025
-120.8%
Dec 2024
-114.9%
Sep 2024
-98.7%
At each fiscal year end
Trailing four quarters at each quarter end
P/E, trailing
n/a
trailing loss, a multiple of a loss is not meaningful
P/E, trailing CRIS
FY Dec 2025
n/a
FY Dec 2024
n/a
FY Dec 2023
n/a
FY Dec 2022
n/a
FY Dec 2021
3,808.00x
Jun 2026
n/a
Mar 2026
n/a
Dec 2025
n/a
Sep 2025
n/a
Jun 2025
n/a
Mar 2025
n/a
Dec 2024
n/a
Sep 2024
n/a
At each fiscal year end
Trailing four quarters at each quarter end
Enterprise value
-$4.3M
market value at close 2026-10-26 on 2026-08-11 shares, plus long-term 2021-09-30 (57 months older than the period end) plus current 2025-12-31 (6 months older than the period end), minus cash 2026-06-30
Enterprise value CRIS
FY Dec 2025
$250.9M
FY Dec 2024
$505.7M
FY Dec 2023
$1.5B
FY Dec 2022
$21.2B
FY Dec 2021
$174.4B
Jun 2026
$400.3M
Mar 2026
$424.8M
Dec 2025
$250.9M
Sep 2025
$412.9M
Jun 2025
$482.7M
Mar 2025
$343.4M
Dec 2024
$505.7M
Sep 2024
$632.2M
At each fiscal year end
Trailing four quarters at each quarter end
FCF yield
-3,851%
TTM free cash flow over market value at close 2026-10-26
FCF yield CRIS
FY Dec 2025
-10.6%
FY Dec 2024
-7.6%
FY Dec 2023
-2.6%
FY Dec 2022
-0.3%
FY Dec 2021
-0.0%
Jun 2026
-7.5%
Mar 2026
-6.6%
Dec 2025
-10.6%
Sep 2025
-7.3%
Jun 2025
-6.3%
Mar 2025
-9.4%
Dec 2024
-7.6%
Sep 2024
-6.3%
At each fiscal year end
Trailing four quarters at each quarter end
PEG, trailing
n/a
trailing loss, a multiple of a loss is not meaningful
PEG, trailing CRIS
FY Dec 2025
n/a
FY Dec 2024
n/a
FY Dec 2023
n/a
FY Dec 2022
n/a
FY Dec 2021
n/a
Jun 2026
n/a
Mar 2026
n/a
Dec 2025
n/a
Sep 2025
n/a
Jun 2025
n/a
Mar 2025
n/a
Dec 2024
n/a
Sep 2024
n/a
At each fiscal year end
Trailing four quarters at each quarter end
Price as of 2026-10-26. Hover or tap a tile for its yearly and quarterly history.Method
TTM is four consecutive fiscal quarters; Q4 is the year minus nine months when not filed. Returns use the average of opening and closing balances. EBIT is approximated by operating income. PEG uses trailing EPS growth.
Fundamentals
Annual figures from XBRL filings. Pick a past date to see them as known then.
CRIS ranks highest on financial health (99th percentile) and growth (33rd), and lowest on risk and compliance (18th), among Pharma & Biotech peers.
Profitability
25
Inputs
Return on equityaverage equity is zero or negative
Return on assets-87.8% · 28 pct, sector of 691
Return on invested capitaltax provision or pre-tax income not filed for the four quarters
Return on capital employed-115.6% · 22 pct, sector of 576
Financial health
100
Inputs
Debt to equity0.00x · 100 pct, sector of 352
Cash flow to debtno debt to cover
Growth
33
Inputs
Revenue growth, YoY-13.4% · 33 pct, sector of 505
Backlog growth, YoYno backlog line filed, or no year-earlier backlog
Institutional and government
23
Inputs
Funds adding, latest quarter13 · 23 pct, sector of 698
Congress net buyers, 365dno Congress trades in 365 days
Federal contracts, 180dno federal contracts in 180 days
Lobbying spend, 4 quartersno lobbying filings in the last four quarters
Risk and compliance
18
Inputs
Short interest, % of float+21.5% · 12 pct, sector of 816
Recalls per $1B revenue, 3yrevenue under $50M or not filed, so a count cannot be scaled to size
EPA cases per $1B revenue, 5yrevenue under $50M or not filed, so a count cannot be scaled to size
New text in Risk Factors, latest 10-K+17.2% · 24 pct, sector of 511
2 not measured: Insider conviction, US patents
Insider conviction needs 1 of 2 inputs, 0 present: no Form 4 purchase or sale (code P or S) in 180 days; no insider trades in 180 days
US patents needs 1 of 2 inputs, 0 present: patent data not loaded yet
5 of 7 axes scored. Each is a percentile against sector peers (all companies when the sector is thin); higher is better. An unscored axis is unmeasured, not low. How it is scored
Explore insider trading and ownership data
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