STOCK Act, US House only, disclosed up to 45 days after the trade
Funds added, last quarter
174
13F, latest reported quarter
Conversions, 180 days
10
Codes C/M, not in net · $67.8K priced
What the filings say about XENE
Insiders, 180 days
+$481.3K net bought
2 buyers · 4 sellers · 40% of sales under a 10b5-1 plan
Planned sales (Form 144), 90 days
$1.1M
2 notices
Xenon Pharmaceuticals insider trades (Form 4)
Form 4 buys and sells (codes P and S). Grants, option exercises
and conversions excluded.
Over the last 180 days, Xenon Pharmaceuticals Inc. insiders bought a net $481.3K of stock across 104 Form 4 purchases and sales, with 2 insiders buying. Source: SEC Form 4 filings, as of 2026-10-28.
25 earlier Form 4 trades (code P or S) here by this insider (25 sales), the last on Mar 13, 2026.
The trade is 60.1% of the 49,923 shares held after it.
1 other insider bought within 30 days.
174 funds added in the 13F quarter to Jun 30, 2026.
Insider activity: PRESIDENT & CEO MORTIMER IAN bought about $1.1M of XENE on Sep 30, 2026, the largest insider purchase at the company on our record; 1 other insider bought within 30 days and 174 funds added in the latest 13F quarter.
First Form 4 purchase or sale (code P or S) here by this insider on our record.
The trade is 100.0% of the 15,000 shares held after it.
1 other insider bought within 30 days.
174 funds added in the 13F quarter to Jun 30, 2026.
Insider activity: Chief Financial Officer Kelly Thomas Patrick bought about $559.7K of XENE on Sep 30, 2026, the largest insider purchase at the company on our record; 1 other insider bought within 30 days and 174 funds added in the latest 13F quarter.
4 earlier Form 4 trades (code P or S) here by this insider (1 buy, 3 sales), the last on Mar 13, 2026.
The trade is 907.1% of the 702 shares held after it.
1 other insider sold within 30 days.
174 funds added in the 13F quarter to Jun 30, 2026.
Insider activity: Chief Medical Officer KENNEY CHRISTOPHER JOHN sold about $383.1K of XENE under a 10b5-1 plan on Aug 28, 2026; 1 other insider sold within 30 days and 174 funds added in the latest 13F quarter.
4 earlier Form 4 trades (code P or S) here by this insider (1 buy, 3 sales), the last on Mar 13, 2026.
The trade is 35000.0% of the 2 shares held after it.
1 other insider sold within 30 days.
174 funds added in the 13F quarter to Jun 30, 2026.
Insider activity: Chief Medical Officer KENNEY CHRISTOPHER JOHN sold about $42.7K of XENE under a 10b5-1 plan on Aug 28, 2026; 1 other insider sold within 30 days and 174 funds added in the latest 13F quarter.
5 earlier Form 4 trades (code P or S) here by this insider (5 sales), the last on Jun 5, 2025.
The trade is 534.8% of the 1,870 shares held after it.
1 other insider sold within 30 days.
174 funds added in the 13F quarter to Jun 30, 2026.
Insider activity: Director GANNON STEVEN sold about $640.5K of XENE on Aug 11, 2026; 1 other insider sold within 30 days and 174 funds added in the latest 13F quarter.
104 transactions on record
Since filing: total return from the first close after the filing to the latest close, dividend-adjusted. Not a forecast.
Context lines are counts over the filings above and returns from our own price history, never a price level. Not investment advice.
Nobody has filed for crossing 5%. That is a fact, not missing data.
XENE planned insider sales (Form 144)
Notice of intent to sell, filed before any sale
CHRISTOPHER KENNEY
Filed 2026-08-28
$437.7K
STEVEN GANNON
Filed 2026-08-13
$640.6K
XENE mutual fund holders (N-PORT)
Funds ranked by the share of their own portfolio in this stock (N-PORT).
ALPS Medical Breakthroughs ETF
$4.7M position · as of 2026-05-31
2.9%
NICHOLAS PARTNERS SMALL CAP GROWTH FUND
$3.7M position · as of 2026-06-30
1.9%
Fidelity Disruptive Medicine ETF
$786.3K position · as of 2026-05-31
1.9%
Driehaus Small Cap Growth Fund
$22.5M position · as of 2026-06-30
1.4%
Goldman Sachs Future Health Care Equity ETF
$272.4K position · as of 2026-05-31
1.4%
Baron Health Care Fund
$1.5M position · as of 2026-06-30
1.3%
SEC N-PORT, monthly, about 60 days late · funds ≥ $10M ·
% is the share of the fund's own portfolio
Clinical pipeline
14 registered trials, 9 still running (ClinicalTrials.gov).
A status change is dated here weeks before the press release.
1
Phase 1
0 active
2
Phase 2
1 active
11
Phase 3
8 active
What changed recently
A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder (X-NOVA3)
2026-10-16 · Recruiting → Active Not Recruiting
Phase 3
A Randomized Study of Azetukalner Versus Placebo in Depressive Episodes Associated With
2026-10-14 · Recruiting → Active Not Recruiting
Phase 3
An Open-label Study of Azetukalner in Bipolar I or II Depression (X-CEED-OLE)
2026-10-14 · Enrolling By Invitation → Active Not Recruiting
Phase 3
An Open-Label Study of Azetukalner in Major Depressive Disorder
2026-10-14 · Enrolling By Invitation → Active Not Recruiting
Phase 3
A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder
2026-10-14 · Completion moved 2026-08 → 2026-10
Phase 3
A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder
2026-10-14 · Recruiting → Active Not Recruiting
Phase 3
Matched by sponsor name. Trials run under a subsidiary's
own name are not included.
Live price
Daily candles from TradingView, under their licence. No filings marked.
Why this name is on the desk
Insiders are net buyers of their own stock.
The record shows a net $481.3K bought by insiders over 180 days, 174 funds added last quarter, $1.1M in planned Form 144 sales. Each figure is a federal filing, dated the day it went public.
Ratios from the company's XBRL filings, latest filings
Revenue, TTM
$0
four quarters, 2025-07-01 to 2026-06-30
Revenue, TTM XENE
FY Dec 2025
$7.5M
FY Dec 2024
$0
FY Dec 2023
$9.4M
FY Dec 2022
$9.4M
FY Dec 2021
$18.4M
Jun 2026
$0
Mar 2026
$0
Dec 2025
$0
Sep 2025
$0
Jun 2025
$0
Mar 2025
$7.5M
Dec 2024
$0
Sep 2024
$0
At each fiscal year end
Single quarter
Net margin, TTM
n/a
revenue under $1M, the ratio says nothing
Net margin, TTM XENE
FY Dec 2025
-4,612%
FY Dec 2024
n/a
FY Dec 2023
-1,933%
FY Dec 2022
-1,329%
FY Dec 2021
-427.8%
Jun 2026
n/a
Mar 2026
n/a
Dec 2025
n/a
Sep 2025
n/a
Jun 2025
n/a
Mar 2025
-867.3%
Dec 2024
n/a
Sep 2024
n/a
At each fiscal year end
Single quarter
Free cash flow, TTM
-$338.5M
operating cash flow minus capex, 2025-07-01 to 2026-06-30
Free cash flow, TTM XENE
FY Dec 2025
-$279.9M
FY Dec 2024
-$184.5M
FY Dec 2023
-$156.7M
FY Dec 2022
-$103.9M
FY Dec 2021
-$71.6M
Jun 2026
-$95.7M
Mar 2026
-$89.0M
Dec 2025
-$81.8M
Sep 2025
-$72.0M
Jun 2025
-$64.4M
Mar 2025
-$61.7M
Dec 2024
-$55.2M
Sep 2024
-$50.3M
At each fiscal year end
Single quarter
Debt to equity
0.02x
long-term 2019-12-31 (79 months older than the period end) plus current 2020-03-31 (76 months older than the period end); equity 2026-06-30
Debt to equity XENE
FY Dec 2025
0.05x
FY Dec 2024
0.04x
FY Dec 2023
0.03x
FY Dec 2022
0.04x
FY Dec 2021
0.05x
Jun 2026
0.02x
Mar 2026
0.02x
Dec 2025
0.05x
Sep 2025
0.05x
Jun 2025
0.04x
Mar 2025
0.04x
Dec 2024
0.04x
Sep 2024
0.03x
At each fiscal year end
Trailing four quarters at each quarter end
Cash flow to debt
-12.71x
TTM operating cash flow over long-term 2019-12-31 (79 months older than the period end) plus current 2020-03-31 (76 months older than the period end)
Cash flow to debt XENE
FY Dec 2025
-10.51x
FY Dec 2024
-6.83x
FY Dec 2023
-5.69x
FY Dec 2022
-3.80x
FY Dec 2021
-2.62x
Jun 2026
-12.71x
Mar 2026
-11.53x
Dec 2025
-10.51x
Sep 2025
-9.49x
Jun 2025
-8.66x
Mar 2025
-7.41x
Dec 2024
-6.83x
Sep 2024
-6.11x
At each fiscal year end
Trailing four quarters at each quarter end
Return on equity
-43.6%
TTM net income over average of 2025-06-30 and 2026-06-30
Return on equity XENE
FY Dec 2025
-51.8%
FY Dec 2024
-27.8%
FY Dec 2023
-22.1%
FY Dec 2022
-19.7%
FY Dec 2021
-21.9%
Jun 2026
-43.6%
Mar 2026
-37.5%
Dec 2025
-51.8%
Sep 2025
-45.1%
Jun 2025
-37.6%
Mar 2025
-31.6%
Dec 2024
-27.8%
Sep 2024
-29.8%
At each fiscal year end
Trailing four quarters at each quarter end
Return on assets
-41.5%
TTM net income over average of 2025-06-30 and 2026-06-30
Return on assets XENE
FY Dec 2025
-48.3%
FY Dec 2024
-26.6%
FY Dec 2023
-21.2%
FY Dec 2022
-18.9%
FY Dec 2021
-20.7%
Jun 2026
-41.5%
Mar 2026
-36.0%
Dec 2025
-48.3%
Sep 2025
-42.4%
Jun 2025
-35.7%
Mar 2025
-30.3%
Dec 2024
-26.6%
Sep 2024
-28.3%
At each fiscal year end
Trailing four quarters at each quarter end
Return on invested capital
n/a
pre-tax loss, no effective tax rate to apply
Return on invested capital XENE
FY Dec 2025
n/a
FY Dec 2024
n/a
FY Dec 2023
n/a
FY Dec 2022
n/a
FY Dec 2021
n/a
Jun 2026
n/a
Mar 2026
n/a
Dec 2025
n/a
Sep 2025
n/a
Jun 2025
n/a
Mar 2025
n/a
Dec 2024
n/a
Sep 2024
n/a
At each fiscal year end
Trailing four quarters at each quarter end
Return on capital employed
-46.7%
operating income (EBIT proxy) over average of 2025-06-30 and 2026-06-30 minus current liabilities
Return on capital employed XENE
FY Dec 2025
-55.1%
FY Dec 2024
-32.9%
FY Dec 2023
-25.7%
FY Dec 2022
-20.0%
FY Dec 2021
-21.6%
Jun 2026
-46.7%
Mar 2026
-40.1%
Dec 2025
-55.1%
Sep 2025
-49.5%
Jun 2025
-42.6%
Mar 2025
-36.4%
Dec 2024
-32.9%
Sep 2024
-35.2%
At each fiscal year end
Trailing four quarters at each quarter end
P/E, trailing
n/a
trailing loss, a multiple of a loss is not meaningful
P/E, trailing XENE
FY Dec 2025
n/a
FY Dec 2024
n/a
FY Dec 2023
n/a
FY Dec 2022
n/a
FY Dec 2021
n/a
Jun 2026
n/a
Mar 2026
n/a
Dec 2025
n/a
Sep 2025
n/a
Jun 2025
n/a
Mar 2025
n/a
Dec 2024
n/a
Sep 2024
n/a
At each fiscal year end
Trailing four quarters at each quarter end
Enterprise value
$3.4B
market value at close 2026-10-27 on 2026-08-03 shares, plus long-term 2019-12-31 (79 months older than the period end) plus current 2020-03-31 (76 months older than the period end), minus cash 2026-06-30
Enterprise value XENE
FY Dec 2025
$3.3B
FY Dec 2024
$2.9B
FY Dec 2023
$2.9B
FY Dec 2022
$2.4B
FY Dec 2021
$1.5B
Jun 2026
$5.7B
Mar 2026
$4.3B
Dec 2025
$3.3B
Sep 2025
$3.0B
Jun 2025
$2.3B
Mar 2025
$2.5B
Dec 2024
$2.9B
Sep 2024
$2.9B
At each fiscal year end
Trailing four quarters at each quarter end
FCF yield
-9.7%
TTM free cash flow over market value at close 2026-10-27
FCF yield XENE
FY Dec 2025
-8.1%
FY Dec 2024
-6.2%
FY Dec 2023
-5.2%
FY Dec 2022
-4.2%
FY Dec 2021
-4.4%
Jun 2026
-5.8%
Mar 2026
-6.4%
Dec 2025
-8.1%
Sep 2025
-8.2%
Jun 2025
-9.6%
Mar 2025
-7.8%
Dec 2024
-6.2%
Sep 2024
-5.5%
At each fiscal year end
Trailing four quarters at each quarter end
PEG, trailing
n/a
trailing loss, a multiple of a loss is not meaningful
PEG, trailing XENE
FY Dec 2025
n/a
FY Dec 2024
n/a
FY Dec 2023
n/a
FY Dec 2022
n/a
FY Dec 2021
n/a
Jun 2026
n/a
Mar 2026
n/a
Dec 2025
n/a
Sep 2025
n/a
Jun 2025
n/a
Mar 2025
n/a
Dec 2024
n/a
Sep 2024
n/a
At each fiscal year end
Trailing four quarters at each quarter end
Price as of 2026-10-27. Hover or tap a tile for its yearly and quarterly history.Method
TTM is four consecutive fiscal quarters; Q4 is the year minus nine months when not filed. Returns use the average of opening and closing balances. EBIT is approximated by operating income. PEG uses trailing EPS growth.
Fundamentals
Annual figures from XBRL filings. Pick a past date to see them as known then.
XENE ranks highest on institutional and government (86th percentile) and insider conviction (84th), and lowest on risk and compliance (44th), among Pharma & Biotech peers.
Profitability
54
Inputs
Return on equity-43.6% · 58 pct, sector of 545
Return on assets-41.5% · 51 pct, sector of 691
Return on invested capitalpre-tax loss, no effective tax rate to apply
Return on capital employed-46.7% · 54 pct, sector of 576
Financial health
46
Inputs
Debt to equity0.02x · 71 pct, sector of 352
Cash flow to debt-12.71x · 22 pct, sector of 371
Insider conviction
84
Inputs
Net Form 4 buying (codes P and S), 180d$907K · 87 pct, sector of 428
Insider buyers, 180d2 · 81 pct, sector of 437
Institutional and government
86
Inputs
Funds adding, latest quarter174 · 86 pct, sector of 698
Congress net buyers, 365dno Congress trades in 365 days
Federal contracts, 180dno federal contracts in 180 days
Lobbying spend, 4 quartersno lobbying filings in the last four quarters
Risk and compliance
44
Inputs
Short interest, % of float+6.7% · 50 pct, sector of 813
Recalls per $1B revenue, 3yrevenue under $50M or not filed, so a count cannot be scaled to size
EPA cases per $1B revenue, 5yrevenue under $50M or not filed, so a count cannot be scaled to size
New text in Risk Factors, latest 10-K+13.1% · 38 pct, sector of 511
2 not measured: Growth, US patents
Growth needs 1 of 2 inputs, 0 present: no backlog line filed, or no year-earlier backlog; no revenue for this year and the year before
US patents needs 1 of 2 inputs, 0 present: patent data not loaded yet
5 of 7 axes scored. Each is a percentile against sector peers (all companies when the sector is thin); higher is better. An unscored axis is unmeasured, not low. How it is scored
XENE filings, in plain words
Are Xenon Pharmaceuticals insiders buying or selling XENE?
In the 180 days to 2026-10-28, Xenon Pharmaceuticals insiders were net buyers, a net $481.3K: $1.7M of purchases and $1.2M of sales reported on Form 4, by 2 buyers and 4 sellers.
Are there planned insider sales of XENE?
Yes. 2 Form 144 notices of planned insider sales were filed in the 90 days to 2026-10-28, covering $1.1M of stock; the latest, by CHRISTOPHER KENNEY, was filed 2026-08-28.
Read the full summary
In the 180 days to 2026-10-28, Xenon Pharmaceuticals insiders were net buyers of XENE, a net $481.3K across purchases and sales reported on Form 4 by 2 buyers and 4 sellers. 2 different insiders reported purchases within the last 90 days, a cluster buy, which is rarer than a single purchase. 40% of the 5 insider sales were made under a Rule 10b5-1 plan; the rest were not flagged as planned. Insiders filed 2 Form 144 notices of intent to sell in the 90 days to 2026-10-28, covering $1.1M of stock. Each figure is counted from SEC and House filings as of 2026-10-28, dated the day the filing was made public.
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