STOCK Act, US House only, disclosed up to 45 days after the trade
Funds added, last quarter
0
13F, latest reported quarter
What the filings say about SHPH
Insiders, 180 days
-$323.1K net sold
1 buyer · 1 seller · 0% of sales under a 10b5-1 plan
Shuttle Pharmaceuticals insider trades (Form 4)
Form 4 buys and sells (codes P and S). Grants, option exercises
and conversions excluded.
Over the last 180 days, Shuttle Pharmaceuticals Holdings, Inc. insiders sold a net $323.1K of stock across 23 Form 4 purchases and sales, with 1 insider buying. Source: SEC Form 4 filings, as of 2026-10-28.
Ratios from the company's XBRL filings, latest filings
Revenue, TTM
n/a
fewer than four consecutive quarters of revenue filed
Revenue, TTM SHPH
FY Dec 2025
n/a
FY Dec 2024
n/a
FY Dec 2023
n/a
FY Dec 2022
n/a
FY Dec 2021
n/a
Jun 2026
n/a
Mar 2026
n/a
Dec 2025
n/a
Sep 2025
n/a
Jun 2025
n/a
Mar 2025
n/a
Dec 2024
n/a
Sep 2024
n/a
At each fiscal year end
Single quarter
Net margin, TTM
n/a
needs four consecutive quarters of both revenue and net income
Net margin, TTM SHPH
FY Dec 2025
n/a
FY Dec 2024
n/a
FY Dec 2023
n/a
FY Dec 2022
n/a
FY Dec 2021
n/a
Jun 2026
n/a
Mar 2026
n/a
Dec 2025
n/a
Sep 2025
n/a
Jun 2025
n/a
Mar 2025
n/a
Dec 2024
n/a
Sep 2024
n/a
At each fiscal year end
Single quarter
Free cash flow, TTM
n/a
capex not filed for the four quarters
Free cash flow, TTM SHPH
FY Dec 2025
n/a
FY Dec 2024
n/a
FY Dec 2023
n/a
FY Dec 2022
n/a
FY Dec 2021
n/a
Jun 2026
n/a
Mar 2026
n/a
Dec 2025
n/a
Sep 2025
n/a
Jun 2025
n/a
Mar 2025
n/a
Dec 2024
n/a
Sep 2024
n/a
At each fiscal year end
Single quarter
Debt to equity
0.00x
long-term debt only, 2021-12-31 (54 months older than the period end); equity 2026-06-30
Debt to equity SHPH
FY Dec 2025
0.04x
FY Dec 2024
0.13x
FY Dec 2023
0.02x
FY Dec 2022
0.01x
FY Dec 2021
n/a
Jun 2026
0.00x
Mar 2026
0.03x
Dec 2025
0.04x
Sep 2025
0.07x
Jun 2025
0.03x
Mar 2025
0.03x
Dec 2024
0.13x
Sep 2024
n/a
At each fiscal year end
Trailing four quarters at each quarter end
Cash flow to debt
-72.34x
TTM operating cash flow over long-term debt only, 2021-12-31 (54 months older than the period end)
Cash flow to debt SHPH
FY Dec 2025
-104.17x
FY Dec 2024
-80.50x
FY Dec 2023
-61.32x
FY Dec 2022
-29.29x
FY Dec 2021
n/a
Jun 2026
-72.34x
Mar 2026
-102.97x
Dec 2025
-104.17x
Sep 2025
-123.04x
Jun 2025
-116.14x
Mar 2025
-94.65x
Dec 2024
-80.50x
Sep 2024
-62.61x
At each fiscal year end
Trailing four quarters at each quarter end
Return on equity
-90.1%
TTM net income over average of 2025-06-30 and 2026-06-30
Return on equity SHPH
FY Dec 2025
-791.0%
FY Dec 2024
-383.8%
FY Dec 2023
-112.4%
FY Dec 2022
-169.0%
FY Dec 2021
n/a
Jun 2026
-90.1%
Mar 2026
-326.3%
Dec 2025
-791.0%
Sep 2025
-27,176%
Jun 2025
-551.0%
Mar 2025
-346.2%
Dec 2024
-383.8%
Sep 2024
-427.9%
At each fiscal year end
Trailing four quarters at each quarter end
Return on assets
-72.5%
TTM net income over average of 2025-06-30 and 2026-06-30
Return on assets SHPH
FY Dec 2025
-180.6%
FY Dec 2024
-216.2%
FY Dec 2023
-90.3%
FY Dec 2022
-107.4%
FY Dec 2021
-176.8%
Jun 2026
-72.5%
Mar 2026
-126.4%
Dec 2025
-180.6%
Sep 2025
-507.8%
Jun 2025
-292.0%
Mar 2025
-208.0%
Dec 2024
-216.2%
Sep 2024
-228.3%
At each fiscal year end
Trailing four quarters at each quarter end
Return on invested capital
n/a
tax provision or pre-tax income not filed for the four quarters
Return on invested capital SHPH
FY Dec 2025
n/a
FY Dec 2024
n/a
FY Dec 2023
n/a
FY Dec 2022
n/a
FY Dec 2021
n/a
Jun 2026
n/a
Mar 2026
n/a
Dec 2025
n/a
Sep 2025
n/a
Jun 2025
n/a
Mar 2025
n/a
Dec 2024
n/a
Sep 2024
n/a
At each fiscal year end
Trailing four quarters at each quarter end
Return on capital employed
-97.0%
operating income (EBIT proxy) over average of 2025-06-30 and 2026-06-30 minus current liabilities
Return on capital employed SHPH
FY Dec 2025
-684.6%
FY Dec 2024
-261.7%
FY Dec 2023
-93.6%
FY Dec 2022
-76.7%
FY Dec 2021
n/a
Jun 2026
-97.0%
Mar 2026
-318.1%
Dec 2025
-684.6%
Sep 2025
-3,682%
Jun 2025
-446.2%
Mar 2025
-272.7%
Dec 2024
-261.7%
Sep 2024
-258.1%
At each fiscal year end
Trailing four quarters at each quarter end
P/E, trailing
n/a
trailing loss, a multiple of a loss is not meaningful
P/E, trailing SHPH
FY Dec 2025
n/a
FY Dec 2024
n/a
FY Dec 2023
n/a
FY Dec 2022
n/a
FY Dec 2021
n/a
Jun 2026
n/a
Mar 2026
n/a
Dec 2025
n/a
Sep 2025
n/a
Jun 2025
n/a
Mar 2025
n/a
Dec 2024
n/a
Sep 2024
n/a
At each fiscal year end
Trailing four quarters at each quarter end
Enterprise value
$24.0M
market value at close 2026-10-26 on 2026-09-21 shares, plus long-term debt only, 2021-12-31 (54 months older than the period end), minus cash 2026-06-30
Enterprise value SHPH
FY Dec 2025
$28.6M
FY Dec 2024
$785.2M
FY Dec 2023
$14.6B
FY Dec 2022
$53.3B
FY Dec 2021
n/a
Jun 2026
$19.0M
Mar 2026
$37.0M
Dec 2025
$28.6M
Sep 2025
$36.0M
Jun 2025
$408.8M
Mar 2025
$392.0M
Dec 2024
$785.2M
Sep 2024
$740.4M
At each fiscal year end
Trailing four quarters at each quarter end
FCF yield
n/a
capex not filed for the four quarters
FCF yield SHPH
FY Dec 2025
n/a
FY Dec 2024
n/a
FY Dec 2023
n/a
FY Dec 2022
n/a
FY Dec 2021
n/a
Jun 2026
n/a
Mar 2026
n/a
Dec 2025
n/a
Sep 2025
n/a
Jun 2025
n/a
Mar 2025
n/a
Dec 2024
n/a
Sep 2024
n/a
At each fiscal year end
Trailing four quarters at each quarter end
PEG, trailing
n/a
trailing loss, a multiple of a loss is not meaningful
PEG, trailing SHPH
FY Dec 2025
n/a
FY Dec 2024
n/a
FY Dec 2023
n/a
FY Dec 2022
n/a
FY Dec 2021
n/a
Jun 2026
n/a
Mar 2026
n/a
Dec 2025
n/a
Sep 2025
n/a
Jun 2025
n/a
Mar 2025
n/a
Dec 2024
n/a
Sep 2024
n/a
At each fiscal year end
Trailing four quarters at each quarter end
Price as of 2026-10-26. Hover or tap a tile for its yearly and quarterly history.Method
TTM is four consecutive fiscal quarters; Q4 is the year minus nine months when not filed. Returns use the average of opening and closing balances. EBIT is approximated by operating income. PEG uses trailing EPS growth.
Fundamentals
Annual figures from XBRL filings. Pick a past date to see them as known then.
SHPH ranks highest on risk and compliance (84th percentile) and insider conviction (51st), and lowest on profitability (32nd), among Pharma & Biotech peers.
Profitability
32
Inputs
Return on equity-90.1% · 36 pct, sector of 545
Return on assets-72.5% · 33 pct, sector of 691
Return on invested capitaltax provision or pre-tax income not filed for the four quarters
Return on capital employed-97.0% · 26 pct, sector of 576
Financial health
45
Inputs
Debt to equity0.00x · 80 pct, sector of 352
Cash flow to debt-72.34x · 9 pct, sector of 371
Insider conviction
51
Inputs
Net Form 4 buying (codes P and S), 180d-$323K · 46 pct, sector of 429
Insider buyers, 180d1 · 56 pct, sector of 438
Risk and compliance
84
Inputs
Short interest, % of float+0.7% · 84 pct, sector of 816
Recalls per $1B revenue, 3yrevenue under $50M or not filed, so a count cannot be scaled to size
EPA cases per $1B revenue, 5yrevenue under $50M or not filed, so a count cannot be scaled to size
New text in Risk Factors, latest 10-Kneeds two 10-Ks with a Risk Factors section (not 20-F filers or stubs)
3 not measured: Growth, Institutional and government, US patents
Growth needs 1 of 2 inputs, 0 present: no backlog line filed, or no year-earlier backlog; no revenue for this year and the year before
Institutional and government needs 1 of 4 inputs, 0 present: fewer than five funds report holding it; no Congress trades in 365 days; no federal contracts in 180 days; no lobbying filings in the last four quarters
US patents needs 1 of 2 inputs, 0 present: patent data not loaded yet
4 of 7 axes scored. Each is a percentile against sector peers (all companies when the sector is thin); higher is better. An unscored axis is unmeasured, not low. How it is scored
SHPH filings, in plain words
Are Shuttle Pharmaceuticals insiders buying or selling SHPH?
In the 180 days to 2026-10-28, Shuttle Pharmaceuticals insiders were net sellers, a net $323.1K: $181.8K of purchases and $504.8K of sales reported on Form 4, by 1 buyer and 1 seller.
Read the full summary
In the 180 days to 2026-10-28, Shuttle Pharmaceuticals insiders were net sellers of SHPH, a net $323.1K across purchases and sales reported on Form 4 by 1 buyer and 1 seller. Most of that figure, $323.1K, came from a holder of 10% or more rather than an officer or director. None of the 5 insider sales was flagged as made under a Rule 10b5-1 plan. Each figure is counted from SEC and House filings as of 2026-10-28, dated the day the filing was made public.
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