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KRYS · Krystal Biotech, Inc.
> Ask across nine datasets ⌘K
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TEAM-2.62% 13F +440META+1.00% 13F +2,694RCG+0.35% CLUSTERUTHR-0.54% 13F +425CRWV+5.68% 13F +694CRM-1.97% 13F +1,019CVNA+1.58% 13F +795TPL-1.11% 13F +444NET-1.96% 13F +711MSTR-1.39% 13F +527DELL+1.50% 13F +1,204CRWD-0.87% 13F +1,383ANET+1.22% 13F +1,324COIN-4.18% 13F +475TEAM-2.62% 13F +440META+1.00% 13F +2,694RCG+0.35% CLUSTERUTHR-0.54% 13F +425CRWV+5.68% 13F +694CRM-1.97% 13F +1,019CVNA+1.58% 13F +795TPL-1.11% 13F +444NET-1.96% 13F +711MSTR-1.39% 13F +527DELL+1.50% 13F +1,204CRWD-0.87% 13F +1,383ANET+1.22% 13F +1,324COIN-4.18% 13F +475
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KRYS

Krystal Biotech, Inc.
PHARMA & BIOTECH · BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES) · CIK 0001711279
FORM 144 · 4☆ WATCH
INSIDER NET · 180D
-$42.1M
open-market buys minus sells, Form 4 codes P and S
INSIDER BUYERS · 180D
0
CONGRESS BUYERS · 1Y
0
FUNDS ADDED · QTR
273
13F, latest reported quarter
REVENUE GROWTH
+33.9%
XBRL, annual
NET MARGIN
52.6%
CONVERSIONS · 180D
1
codes C/M, not in net · $179.2K priced
SEVEN FACTS, RANKED AGAINST THE SECTOR · RANK IS NOT A FORECAST
INSIDERS
net -$42.1M over 180 days
-$26.5M over 90 days · -$33.4M of it by a 10%+ holder
below 93% of Pharma & Biotech
CONGRESS
no member of Congress has reported trading it
FUNDS
273 funds added or opened last quarter
more than 92% of Pharma & Biotech
REVENUE
+33.9% year over year
more than 75% of Pharma & Biotech
MARGIN
52.6% net margin
more than 96% of Pharma & Biotech
BUYBACKS
no share repurchases reported
SHORT
10.8% of shares outstanding short · 4.2 days to cover · settled 2026-07-31
more than 80% of Pharma & Biotech
THE SITUATION · EVERY LINE IS ONE RULE OVER ONE DATASET
Insiders are net sellers: -$42.1M across 4 people in 180 days.
273 funds added or opened positions in the latest 13F quarter, of 427 holders.
The year, with the filings on it
Total return indexed to 100 over the last 12 months · every marker is a federal filing, placed at its date — hover any marker for the detail
TOTAL 12M RETURN +140.4%
+140.4%12M
-8%+46%+100%+154%2025-092025-102025-122026-032026-052026-072026-09 2026-06-04 · Krishnan Suma sold $3.9M2026-06-04 · Krishnan Krish S sold $3.5M2026-02-24 · JANNEY DANIEL sold $3.1M2026-02-19 · ROSSI DINO A sold $2.8M2026-02-27 · JANNEY DANIEL sold $2.6M2026-08-14 · ROSSI DINO A sold $2.4M2026-02-24 · JANNEY DANIEL sold $2.4M2026-03-04 · Krishnan Krish S sold $2.3M2025-12-04 · Krishnan Suma sold $2.3M2025-12-04 · Krishnan Krish S sold $2.3M2025-12-04 · Krishnan Suma sold $2.3M2025-12-04 · Krishnan Krish S sold $2.3M2026-02-19 · ROSSI DINO A sold $2.1M2026-02-24 · JANNEY DANIEL sold $1.8M2026-08-14 · ROSSI DINO A sold $1.7M2026-08-14 · ROSSI DINO A sold $1.6M2026-03-04 · Krishnan Suma sold $1.6M2026-02-09 · ROMANO KATHRYN sold $1.5M2026-06-04 · Krishnan Krish S sold $1.5M2026-09-04 · Krishnan Krish S sold $1.4M2026-09-04 · Krishnan Suma sold $1.4M2026-02-26 · JANNEY DANIEL sold $1.4M2026-03-04 · Krishnan Suma sold $1.3M2025-12-04 · Krishnan Krish S sold $1.2M2025-12-04 · Krishnan Suma sold $1.2M2026-09-04 · Krishnan Suma sold $1.2M2026-09-04 · Krishnan Krish S sold $1.2M2025-12-04 · Krishnan Suma sold $1.2M2025-12-04 · Krishnan Krish S sold $1.2M2026-09-04 · Krishnan Krish S sold $1.2M2026-06-04 · Krishnan Suma sold $1.2M2026-09-04 · Krishnan Suma sold $1.2M2026-02-24 · JANNEY DANIEL sold $1.2M2026-09-04 · Krishnan Suma sold $1.1M2026-09-04 · Krishnan Krish S sold $1.1M2026-02-24 · JANNEY DANIEL sold $1.1M2026-08-14 · ROSSI DINO A sold $1.0M2026-03-04 · Krishnan Suma sold $954.8K2026-02-24 · JANNEY DANIEL sold $942.9K2026-06-04 · Krishnan Suma sold $868.2K2026-06-04 · Krishnan Krish S sold $861.6K2026-09-04 · Krishnan Suma sold $836.3K2026-09-04 · KRISH KRISHNAN filed to sell $9.3M2026-09-04 · SUMA KRISHNAN filed to sell $9.3M2026-08-14 · Dino A. Rossi filed to sell $8.3M2026-06-25 · Thomas John Charles filed to sell $347.3K
INSIDER SELLFORM 144
INDEXED RETURN, DIVIDEND-ADJUSTED — NOT A PRICE CHART · LARGE TRADES DRAWN FIRST WHEN A NAME FILES HEAVILY
Live price
Daily candles from TradingView, on their licence — no filings are marked on this one
WHY THIS NAME IS ON THE DESK
Insiders have filed to sell — before selling.
The record shows a net $42.1M sold by insiders over 180 days, 273 funds added last quarter, $27.2M in planned Form 144 sales. Every figure is a federal filing, dated the day it became public.
Backtest this pattern Open the screener
Same sector, ranked by filing activity
Sector from the SEC's own SIC classification
UTHRCPIXMRNAREGNLLYALNYELFCITRMDGLDNAVRTXNUVL
Insider transactions
Form 4 purchases and sales (codes P and S) — grants, option exercises and preferred conversions excluded

Over the last 180 days, Krystal Biotech, Inc. insiders sold a net $42.1M of stock across 476 Form 4 purchases and sales, with 0 insider(s) buying. Source: SEC Form 4 filings, as of 2026-09-06.

INSIDER
FILED
SHARES
VALUE
Krishnan Krish S
President and CEO
SELL
2026-09-04
520.0
$184.4K
Krishnan Krish S
President and CEO
SELL
2026-09-04
2,029.0
$721.5K
Krishnan Krish S
President and CEO
SELL
2026-09-04
3,297.0
$1.2M
Krishnan Krish S
President and CEO
SELL
2026-09-04
3,981.0
$1.4M
Krishnan Krish S
President and CEO
SELL
2026-09-04
3,143.0
$1.1M
476 TRANSACTIONS ON RECORD

Showing the most recent few. Create a free account to see 471 more transactions on record, the cross-source screener and CSV export. We store only your email address, and there is no password to create.

Institutional holders
13F · holdings as of the latest quarter funds have reported
FMR LLC
4,418,197.0 sh
$1.6B
BlackRock, Inc.
4,181,432.0 sh
$1.6B
Avoro Capital Advisors LLC
2,888,888.0 sh
$1.1B
VANGUARD PORTFOLIO MANAGEMENT LLC
1,574,905.0 sh
$585.3M
STATE STREET CORP
1,351,158.0 sh
$502.2M
SCHEDULE 13D/G
No 5%+ ownership filings
Nobody has crossed 5% with a filing obligation. Absence is a fact here, not missing data.
Planned sales · Form 144
Filed before the sale — intent, not a trade
KRISH KRISHNAN
FILED 2026-09-04
$9.3M
SUMA KRISHNAN
FILED 2026-09-04
$9.3M
Dino A. Rossi
FILED 2026-08-14
$8.3M
Thomas John Charles
FILED 2026-06-25
$347.3K
Fund concentration
N-PORT · funds ranked by how much of THEMSELVES they put in this stock — the conviction number 13F cannot show
Select Biotechnology Portfolio
$497.9M POSITION · AS OF 2026-02-28
9.3%
EVOLUTIONARY TREE INNOVATORS FUND
$1.1M POSITION · AS OF 2026-02-28
5.4%
Franklin Genomic Advancements ETF
$1.1M POSITION · AS OF 2026-03-31
5.3%
Biondo Focus Fund
$2.1M POSITION · AS OF 2026-03-31
4.7%
Invesco S&P SmallCap Health Care ETF
$5.9M POSITION · AS OF 2026-02-28
4.2%
First Trust NYSE Arca Biotechnology Index Fund
$79.7M POSITION · AS OF 2026-03-31
3.5%
SEC N-PORT, MONTHLY WITH A ~60-DAY PUBLIC LAG · FUNDS ≥ $10M · % = SHARE OF THE FUND'S OWN BOOK
Clinical pipeline
ClinicalTrials.gov · 15 registered trials, 10 still enrolling or running — a status change here is dated weeks before the press release
4
Phase 1
3 ACTIVE
1
Phase 2
0 ACTIVE
3
Phase 3
1 ACTIVE
1
Early Phase 1
1 ACTIVE
1
Not applicable
1 ACTIVE
5
Multi-phase
4 ACTIVE
TRIALS MATCHED TO THIS TICKER BY SPONSOR NAME · STUDIES RUN UNDER A SUBSIDIARY'S OWN NAME ARE NOT INCLUDED
Executive pay vs shareholder return · Mr. Krishnan
DEF 14A pay-versus-performance disclosure · both the headline pay and the SEC's mark-to-market figure, beside the return the company delivered and the return of the peer group it chose itself
FY
CEO TOTAL
ACTUALLY PAID
OTHER NEOs AVG
TSR
PEER TSR
2025
$10.4M
$22.8M
$4.6M
+311%
+20%
2024
$15.6M
$19.8M
$5.6M
+183%
+14%
2023
$6.2M
$11.7M
$2.9M
+124%
+15%
2022
$3.3M
$4.3M
$2.8M
+43%
+11%
2021
$7.4M
$6.8M
$5.9M
+26%
+25%
TAGGED BY THE COMPANY UNDER SEC ITEM 402(v) · RETURN IS CUMULATIVE FROM THE START OF THE DISCLOSURE PERIOD · GREEN WHERE THE COMPANY BEAT ITS OWN PEER GROUP
Fundamentals
Annual figures from XBRL filings · pick a past date to see them exactly as the market knew them then — restatements and all
2025-122024-122023-122022-12
REVENUE$389.1M$290.5M$50.7M$0
OPERATING INCOME$161.3M$65.7M$-109.6M$-145.2M
NET INCOME$204.8M$89.2M$10.9M$-140.0M
EPS (DILUTED)6.843.000.39-5.49
OPERATING CASH FLOW$200.9M$123.4M$-88.8M$-100.6M
CASH$496.3M$344.9M$358.3M$161.9M
SEC XBRL · FISCAL-YEAR PERIODS · AS KNOWN ON 2026-09-06 · NOBODY ELSE SHOWS FUNDAMENTALS AS OF A PAST DATE
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Public filings, honestly analyzed. Official US government sources in one desk — every figure carries the date it was filed, and the methodology is published, backtest included.

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© 2026 WAVEMAN · SOURCE: SEC EDGAR & OFFICIAL GOVERNMENT DATA · NOT INVESTMENT ADVICE · CHART BY TRADINGVIEW · UPDATED 2026-09-06 ALL SYSTEMS LIVE FOR MACHINES →