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Knott David M Jr 13F holdings
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Knott David M Jr 13F holdings

Knott David M Jr reported 83 positions with a total reported value of $189.2M as of 2026-06-30, in its 13F for Q2 2026, filed 2026-08-12. Top holdings by reported value: GOOGL Alphabet Inc CL A (17.1%), APO Apollo Global Management, Inc. (14.1%), SNDX Syndax Pharmaceutical, Inc. (5.1%), XERS Xeris Biopharma Holdings, Inc. (4.4%), TVTX Travere Therapeutics, Inc. (4.4%). Against 2026-03-31 it opened 9 new positions and exited 10. Next 13F due by 2026-11-14, the legal deadline 45 days after the quarter ending 2026-09-30.

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Top holdings

25 largest of 83 positions · reported value as of 2026-06-30
HoldingSharesReported value% of portfolio
GOOGL Alphabet Inc CL A91,720$32.4M17.1%
APO Apollo Global Management, Inc.225,000$26.6M14.1%
SNDX Syndax Pharmaceutical, Inc.437,245$9.6M5.1%
XERS Xeris Biopharma Holdings, Inc.1,060,000$8.4M4.4%
TVTX Travere Therapeutics, Inc.147,282$8.4M4.4%
PTGX Protagonist Therapeutics, Inc63,000$7.7M4.1%
BBIO Bridgebio Pharma, Inc.92,850$6.9M3.7%
IOVA Iovance Biotherapeutics, Inc.1,600,000$6.7M3.5%
ALKS Alkermes PLC121,759$6.4M3.4%
JPM JPMorgan Chase & Co.18,098$5.9M3.1%
Janus Henderson AAA CLO ETF93,528$4.7M2.5%
LPLA LPL Financial Holdings Inc.16,500$4.6M2.5%
COGT Cogent Biosciences Inc.111,081$4.3M2.3%
TGTX TG Therapeutics, Inc.66,839$3.7M1.9%
CLST Catalyst Pharmaceuticals, Inc.114,000$3.6M1.9%
AGIO Agios Pharmaceutical, Inc.95,058$3.5M1.9%
Viridian Therapeutics, Inc.181,000$3.3M1.8%
RLMD Relmada Therapeutics, Inc.451,000$3.1M1.6%
RCUS Arcus Biosciences, Inc.81,241$2.5M1.3%
Cybin Inc370,000$2.4M1.3%
SPDR S&P Biotech ETF15,000$2.4M1.3%
RZLT Rezolute, Inc.370,000$1.9M1.0%
AB AllianceBernstein Holding L.P.48,000$1.7M0.9%
MDGL Madrigal Pharmaaceuticals, Inc.3,000$1.6M0.9%
ATRC AtriCure, Inc.51,400$1.4M0.8%
SEC FORM 13F · Q2 2026 · VALUES AS REPORTED, NOT PRICES

New positions this quarter

Held at 2026-06-30, not at 2026-03-31 · 9 in all · reported value as of 2026-06-30
HoldingSharesReported value% of portfolio
CLST Catalyst Pharmaceuticals, Inc.114,000$3.6M1.9%
SPRB Spruce Biosciences, Inc.20,000$1.1M0.6%
INSM Insmed Incorporated4,253$453.5K0.2%
LBRX LB Pharmaceuticals, Inc.12,965$420.8K0.2%
CDNA CareDx, Inc.13,630$388.5K0.2%
QTTB Q32 Bio Inc30,412$387.4K0.2%
ELVN Enliven Therapeutics, Inc.6,183$313.8K0.2%
BSX Boston Scientific Corporation6,000$256.1K0.1%
Occidential Pertro Wts exp. 8/3/27194$4.3K<0.1%

Sold out

Held at 2026-03-31, gone by 2026-06-30 · 10 in all · reported value as of 2026-03-31
HoldingShares 2026-03-31Reported value% of portfolio then
CPRX Catalyst Pharmaceuticals, Inc.120,000$3.0M1.8%
Arcellx Inc19,433$2.2M1.3%
CYTK Cytokinetics, Incorporated23,644$1.6M0.9%
Centessa Pharmaceuticals PLC39,000$1.5M0.9%
ADMA ADMA Biologics, Inc.60,200$542.4K0.3%
Biohaven Pharmaceutical Holding Co. Ltd60,720$513.7K0.3%
EOLS Evolus, Inc.99,338$408.3K0.2%
LENZ LENZ Therapeutics, Inc.33,732$308.6K0.2%
JSPR Jasper Therapeutics, Inc.160,789$140.9K<0.1%
MREO Mereo BioPharm Group PLC300,337$99.1K<0.1%

Biggest increases and decreases

Positions held at both quarter ends, by change in shares · reported value as of 2026-06-30

Increases

HoldingShares 2026-03-31Shares 2026-06-30ChangeReported value
CGEM Cullinan Therapeutics, Inc.24,20069,182+185.9%$1.3M
MDGL Madrigal Pharmaaceuticals, Inc.2,0003,000+50.0%$1.6M
TVTX Travere Therapeutics, Inc.140,633147,282+4.7%$8.4M
SNDX Syndax Pharmaceutical, Inc.422,000437,245+3.6%$9.6M
ARDX Ardelyx, Inc.207,000263,168+27.1%$1.3M
COGT Cogent Biosciences Inc.104,000111,081+6.8%$4.3M
BBIO Bridgebio Pharma, Inc.90,00092,850+3.2%$6.9M
VSTM Verastem Inc.104,000155,000+49.0%$592.1K
RARE Ultragenyx Pharmaceutical Inc.33,06938,069+15.1%$1.3M
CNTB Connect Biopharma Holdings Limited387,835444,862+14.7%$1.1M
Cybin Inc350,000370,000+5.7%$2.4M
ALKS Alkermes PLC120,000121,759+1.5%$6.4M

Decreases

HoldingShares 2026-03-31Shares 2026-06-30ChangeReported value
TGTX TG Therapeutics, Inc.90,00166,839-25.7%$3.7M
BMY Bristol-Myers Squibb Company13,6222,000-85.3%$115.2K
JPM JPMorgan Chase & Co.19,47718,098-7.1%$5.9M
Occidental Petroleum Corporation663469-29.3%$22.8K
CIK 1892770 · 13F FILINGS ON EDGAR · INFORMATIONAL ONLY

Source: U.S. Securities and Exchange Commission (EDGAR) and other official government data · Updated 2026-10-28 · For informational purposes only, not investment advice.
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