Ikarian Capital, LLC 13F holdings
Ikarian Capital, LLC reported 126 positions with a total reported value of $610.9M as of 2026-06-30, in its 13F for Q2 2026, filed 2026-08-14. Top holdings by reported value: ABVX ABIVAX SA (7.1%), KOD KODIAK SCIENCES INC (6.8%), ALMS ALUMIS INC (4.0%), PRAX PRAXIS PRECISION MEDICINES I (4.0%), PCVX VAXCYTE INC (3.7%). Against 2026-03-31 it opened 26 new positions and exited 27. Next 13F due by 2026-11-14, the legal deadline 45 days after the quarter ending 2026-09-30.
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Top holdings
25 largest of 126 positions · reported value as of 2026-06-30
| Holding | Shares | Reported value | % of portfolio |
|---|---|---|---|
| ABVX ABIVAX SA | 328,635 | $43.4M | 7.1% |
| KOD KODIAK SCIENCES INC | 1,059,730 | $41.3M | 6.8% |
| ALMS ALUMIS INC | 870,548 | $24.5M | 4.0% |
| PRAX PRAXIS PRECISION MEDICINES I | 72,842 | $24.4M | 4.0% |
| PCVX VAXCYTE INC | 388,682 | $22.6M | 3.7% |
| ANIP ANI PHARMACEUTICALS INC | 272,085 | $22.5M | 3.7% |
| CLDX CELLDEX THERAPEUTICS INC NEW | 478,500 | $17.8M | 2.9% |
| RCUS ARCUS BIOSCIENCES INC | 504,559 | $15.6M | 2.5% |
| RLMD RELMADA THERAPEUTICS INC | 2,148,359 | $14.9M | 2.4% |
| CAPR CAPRICOR THERAPEUTICS INC | 604,215 | $14.5M | 2.4% |
| COGT COGENT BIOSCIENCES INC | 370,084 | $14.3M | 2.3% |
| VERA VERA THERAPEUTICS INC | 310,000 | $13.3M | 2.2% |
| CTNM CONTINEUM THERAPEUTICS INC | 807,874 | $13.2M | 2.2% |
| TENX TENAX THERAPEUTICS INC | 787,600 | $11.5M | 1.9% |
| CCCC C4 THERAPEUTICS INC | 2,433,000 | $11.4M | 1.9% |
| MAZE MAZE THERAPEUTICS INC | 378,999 | $11.3M | 1.9% |
| BHVN BIOHAVEN LTD | 748,181 | $11.1M | 1.8% |
| CNTB CONNECT BIOPHARMA HLDGS LTD | 4,538,534 | $10.8M | 1.8% |
| ANRO ALTO NEUROSCIENCE INC | 407,338 | $10.7M | 1.8% |
| PHVS PHARVARIS N V | 308,856 | $10.7M | 1.7% |
| JBIO JADE BIOSCIENCES INC | 427,349 | $9.5M | 1.6% |
| DMRA DAMORA THERAPEUTICS INC | 335,710 | $8.7M | 1.4% |
| VIRIDIAN THERAPEUTICS INC | 425,000 | $7.8M | 1.3% |
| PTHS PELTHOS THERAPEUTICS INC | 256,598 | $7.3M | 1.2% |
| ZURA ZURA BIO LTD | 1,218,492 | $7.2M | 1.2% |
SEC FORM 13F · Q2 2026 · VALUES AS REPORTED, NOT PRICES
New positions this quarter
Held at 2026-06-30, not at 2026-03-31 · 26 in all · reported value as of 2026-06-30
| Holding | Shares | Reported value | % of portfolio |
|---|---|---|---|
| RCUS ARCUS BIOSCIENCES INC | 504,559 | $15.6M | 2.5% |
| COGT COGENT BIOSCIENCES INC | 370,084 | $14.3M | 2.3% |
| CCCC C4 THERAPEUTICS INC | 2,433,000 | $11.4M | 1.9% |
| VIRIDIAN THERAPEUTICS INC | 425,000 | $7.8M | 1.3% |
| HIMS HIMS & HERS HEALTH INC | 188,381 | $6.5M | 1.1% |
| ELVN ENLIVEN THERAPEUTICS INC | 126,541 | $6.4M | 1.1% |
| KZIA KAZIA THERAPEUTICS LTD | 396,201 | $5.6M | 0.9% |
| QTTB Q32 BIO INC | 430,000 | $5.5M | 0.9% |
| BIOA BIOAGE LABS INC | 200,000 | $4.9M | 0.8% |
| MNPR MONOPAR THERAPEUTICS INC | 47,861 | $4.4M | 0.7% |
| ABSI ABSCI CORPORATION | 353,772 | $4.1M | 0.7% |
| CLYM CLIMB BIO INC | 300,000 | $3.9M | 0.6% |
| CUE CUE BIOPHARMA INC | 104,364 | $3.3M | 0.5% |
| ARWR ARROWHEAD PHARMACEUTICALS IN | 38,278 | $3.1M | 0.5% |
| RNTX REIN THERAPEUTICS INC | 2,950,000 | $3.1M | 0.5% |
| AMLX AMYLYX PHARMACEUTICALS INC | 117,500 | $2.1M | 0.3% |
| AVTX AVALO THERAPEUTICS INC | 90,183 | $1.7M | 0.3% |
| AMAN AMANAT ACQUISITION CORP | 150,000 | $1.5M | 0.2% |
| QUINCE THERAPEUTICS INC | 72,251 | $1.3M | 0.2% |
| IMNM IMMUNOME INC | 60,000 | $1.3M | 0.2% |
| PLRX PLIANT THERAPEUTICS INC | 1,000,000 | $1.1M | 0.2% |
| TRAX FIRST TRACKS BIOTHERAPEUTICS | 42,775 | $860.6K | 0.1% |
| ELTX ELICIO THERAPEUTICS INC | 100,000 | $391.0K | <0.1% |
| INM INMED PHARMACEUTICALS INC | 245,025 | $379.8K | <0.1% |
| BCRX BIOCRYST PHARMACEUTICALS INC | 16,756 | $167.6K | <0.1% |
Sold out
Held at 2026-03-31, gone by 2026-06-30 · 27 in all · reported value as of 2026-03-31
| Holding | Shares 2026-03-31 | Reported value | % of portfolio then |
|---|---|---|---|
| TERNS PHARMACEUTICALS INC | 1,456,378 | $76.8M | 11.0% |
| CYTK CYTOKINETICS INC | 283,572 | $18.7M | 2.7% |
| RVMD REVOLUTION MEDICINES INC | 163,142 | $15.9M | 2.3% |
| ORKA ORUKA THERAPEUTICS INC | 242,021 | $11.9M | 1.7% |
| SOLENO THERAPEUTICS INC | 344,123 | $11.5M | 1.6% |
| IONS IONIS PHARMACEUTICALS INC | 127,038 | $9.5M | 1.4% |
| PVLA PALVELLA THERAPEUTICS INC NE | 64,626 | $8.1M | 1.2% |
| LLY ELI LILLY & CO | 6,547 | $6.0M | 0.9% |
| SRZN SURROZEN INC | 173,107 | $5.0M | 0.7% |
| LEGN LEGEND BIOTECH CORP | 226,888 | $4.1M | 0.6% |
| KPTI KARYOPHARM THERAPEUTICS INC | 733,435 | $4.1M | 0.6% |
| PERCEPTIVE CAP SOLUTIONS COR | 240,951 | $2.6M | 0.4% |
| VIR VIR BIOTECHNOLOGY INC | 293,258 | $2.6M | 0.4% |
| BBOT BRIDGEBIO ONCOLOGY THERAPEUT | 270,231 | $2.4M | 0.3% |
| NUVL NUVALENT INC | 23,594 | $2.4M | 0.3% |
| JAZZ JAZZ PHARMACEUTICALS PLC | 12,460 | $2.4M | 0.3% |
| QURE UNIQURE NV | 91,060 | $1.5M | 0.2% |
| DFTX DEFINIUM THERAPEUTICS INC | 58,803 | $1.1M | 0.2% |
| KEZAR LIFE SCIENCES INC | 102,211 | $758.4K | 0.1% |
| CENTESSA PHARMACEUTICALS PLC | 18,113 | $719.4K | 0.1% |
| KALVISTA PHARMACEUTICALS INC | 35,119 | $706.9K | 0.1% |
| INSM INSMED INC | 4,214 | $689.1K | <0.1% |
| SGMOQ SANGAMO THERAPEUTICS INC | 1,218,671 | $300.9K | <0.1% |
| VERU VERU INC | 133,517 | $295.1K | <0.1% |
| IOBTQ IO BIOTECH INC | 1,386,565 | $81.4K | <0.1% |
Biggest increases and decreases
Positions held at both quarter ends, by change in shares · reported value as of 2026-06-30
Increases
| Holding | Shares 2026-03-31 | Shares 2026-06-30 | Change | Reported value |
|---|---|---|---|---|
| ABVX ABIVAX SA | 57,635 | 328,635 | +470.2% | $43.4M |
| ANIP ANI PHARMACEUTICALS INC | 147,085 | 272,085 | +85.0% | $22.5M |
| BHVN BIOHAVEN LTD | 412,481 | 748,181 | +81.4% | $11.1M |
| RZLT REZOLUTE INC | 16,479 | 935,012 | +5,574.0% | $4.9M |
| VERA VERA THERAPEUTICS INC | 200,000 | 310,000 | +55.0% | $13.3M |
| PROQR THRAPEUTICS N V | 1,492,229 | 3,425,930 | +129.6% | $6.4M |
| PMN PROMIS NEUROSCIENCES INC | 55,000 | 205,000 | +272.7% | $2.7M |
| CAPR CAPRICOR THERAPEUTICS INC | 528,015 | 604,215 | +14.4% | $14.5M |
| TECX TECTONIC THERAPEUTIC INC | 157,537 | 205,837 | +30.7% | $7.1M |
| PALI PALISADE BIO INC | 274,978 | 750,000 | +172.7% | $1.6M |
| FTH FAETH THERAPEUTICS INC | 6,351 | 35,386 | +457.2% | $884.6K |
| CLDX CELLDEX THERAPEUTICS INC NEW | 461,247 | 478,500 | +3.7% | $17.8M |
Decreases
| Holding | Shares 2026-03-31 | Shares 2026-06-30 | Change | Reported value |
|---|---|---|---|---|
| HROW HARROW INC | 543,047 | 135,775 | -75.0% | $5.8M |
| RARE ULTRAGENYX PHARMACEUTICAL IN | 482,571 | 165,617 | -65.7% | $5.5M |
| ALMS ALUMIS INC | 1,213,548 | 870,548 | -28.3% | $24.5M |
| CMPS COMPASS PATHWAYS PLC | 675,000 | 15,000 | -97.8% | $212.2K |
| IMUX IMMUNIC INC | 674,662 | 67,464 | -90.0% | $1.0M |
| KOD KODIAK SCIENCES INC | 1,265,795 | 1,059,730 | -16.3% | $41.3M |
| BBIO BRIDGEBIO PHARMA INC | 160,120 | 57,417 | -64.1% | $4.3M |
| PHVS PHARVARIS N V | 486,856 | 308,856 | -36.6% | $10.7M |
| DRUG BRIGHT MINDS BIOSCIENCES INC | 166,647 | 88,951 | -46.6% | $6.2M |
| RLMD RELMADA THERAPEUTICS INC | 2,688,359 | 2,148,359 | -20.1% | $14.9M |
| TENX TENAX THERAPEUTICS INC | 1,017,600 | 787,600 | -22.6% | $11.5M |
| DCTH DELCATH SYS INC | 431,251 | 185,667 | -56.9% | $2.3M |
CIK 1778253 · 13F FILINGS ON EDGAR · INFORMATIONAL ONLY
