Venrock Adviser, LLC 13F holdings
Venrock Adviser, LLC reported 33 positions with a total reported value of $3.3B as of 2026-06-30, in its 13F for Q2 2026, filed 2026-08-14. Top holdings by reported value: APGE APOGEE THERAPEUTICS INC (34.2%), ORKA ORUKA THERAPEUTICS INC (12.0%), ERAS ERASCA INC (9.9%), SYRE SPYRE THERAPEUTICS INC (8.0%), DNTH DIANTHUS THERAPEUTICS INC (3.5%). Against 2026-03-31 it opened 4 new positions and exited 4. Next 13F due by 2026-11-14, the legal deadline 45 days after the quarter ending 2026-09-30.
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Top holdings
| Holding | Shares | Reported value | % of portfolio |
|---|---|---|---|
| APGE APOGEE THERAPEUTICS INC | 8,493,321 | $1.1B | 34.2% |
| ORKA ORUKA THERAPEUTICS INC | 4,148,428 | $394.8M | 12.0% |
| ERAS ERASCA INC | 17,891,812 | $327.8M | 9.9% |
| SYRE SPYRE THERAPEUTICS INC | 2,985,448 | $265.0M | 8.0% |
| DNTH DIANTHUS THERAPEUTICS INC | 1,180,000 | $115.0M | 3.5% |
| OCUL OCULAR THERAPEUTIX INC | 10,346,926 | $101.6M | 3.1% |
| DMRA DAMORA THERAPEUTICS INC | 3,603,595 | $93.7M | 2.8% |
| SVRA SAVARA INC | 14,745,943 | $90.8M | 2.8% |
| JBIO JADE BIOSCIENCES INC | 3,220,364 | $71.6M | 2.2% |
| COGT COGENT BIOSCIENCES INC | 1,642,166 | $63.6M | 1.9% |
| VIRIDIAN THERAPEUTICS INC | 3,257,917 | $59.8M | 1.8% |
| VOR VOR BIOPHARMA INC | 3,041,719 | $56.0M | 1.7% |
| DYN DYNE THERAPEUTICS INC | 2,173,913 | $48.3M | 1.5% |
| MAZE MAZE THERAPEUTICS INC | 1,602,034 | $47.8M | 1.4% |
| RLMD RELMADA THERAPEUTICS INC | 6,844,305 | $47.4M | 1.4% |
| ORIC ORIC PHARMACEUTICALS INC | 4,319,765 | $46.8M | 1.4% |
| CBIO CRESCENT BIOPHARMA INC. | 2,133,576 | $38.4M | 1.2% |
| ZURA ZURA BIO LTD | 6,434,990 | $38.0M | 1.2% |
| ANL ADLAI NORTYE LTD | 3,212,731 | $36.9M | 1.1% |
| ELVN ENLIVEN THERAPEUTICS INC | 526,331 | $26.7M | 0.8% |
| CYBIN INC | 3,851,654 | $25.5M | 0.8% |
| CGEM CULLINAN THERAPEUTICS INC | 1,379,965 | $25.1M | 0.8% |
| IPSC CENTURY THERAPEUTICS INC | 8,695,652 | $21.3M | 0.6% |
| ARTV ARTIVA BIOTHERAPEUTICS INC | 2,043,596 | $19.8M | 0.6% |
| CTMX CYTOMX THERAPEUTICS INC | 4,982,124 | $18.7M | 0.6% |
New positions this quarter
Sold out
Biggest increases and decreases
Increases
| Holding | Shares 2026-03-31 | Shares 2026-06-30 | Change | Reported value |
|---|---|---|---|---|
| ERAS ERASCA INC | 16,382,812 | 17,891,812 | +9.2% | $327.8M |
| RLMD RELMADA THERAPEUTICS INC | 4,843,380 | 6,844,305 | +41.3% | $47.4M |
| XFOR X4 PHARMACEUTICALS INC | 330,525 | 1,934,253 | +485.2% | $9.0M |
| SVRA SAVARA INC | 13,740,375 | 14,745,943 | +7.3% | $90.8M |
| ARTV ARTIVA BIOTHERAPEUTICS INC | 1,609,569 | 2,043,596 | +27.0% | $19.8M |
Decreases
| Holding | Shares 2026-03-31 | Shares 2026-06-30 | Change | Reported value |
|---|---|---|---|---|
| SYRE SPYRE THERAPEUTICS INC | 3,685,448 | 2,985,448 | -19.0% | $265.0M |
| ELVN ENLIVEN THERAPEUTICS INC | 1,726,331 | 526,331 | -69.5% | $26.7M |
| CTMX CYTOMX THERAPEUTICS INC | 9,982,124 | 4,982,124 | -50.1% | $18.7M |
| COGT COGENT BIOSCIENCES INC | 2,000,000 | 1,642,166 | -17.9% | $63.6M |
| VIRIDIAN THERAPEUTICS INC | 3,882,709 | 3,257,917 | -16.1% | $59.8M |

