Sio Capital Management, LLC 13F holdings
Sio Capital Management, LLC reported 57 positions with a total reported value of $583.5M as of 2026-06-30, in its 13F for Q2 2026, filed 2026-08-14. Top holdings by reported value: AVR ANTERIS TECHNOLOGIES GLOBAL (9.4%), COR CENCORA INC (8.4%), MMS MAXIMUS INC (6.6%), ALLO ALLOGENE THERAPEUTICS INC (4.7%), GMED GLOBUS MED INC (4.1%). Against 2026-03-31 it opened 15 new positions and exited 31. Next 13F due by 2026-11-14, the legal deadline 45 days after the quarter ending 2026-09-30.
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Top holdings
25 largest of 57 positions · reported value as of 2026-06-30
| Holding | Shares | Reported value | % of portfolio |
|---|---|---|---|
| AVR ANTERIS TECHNOLOGIES GLOBAL | 5,545,984 | $54.6M | 9.4% |
| COR CENCORA INC | 173,588 | $49.1M | 8.4% |
| MMS MAXIMUS INC | 715,267 | $38.5M | 6.6% |
| ALLO ALLOGENE THERAPEUTICS INC | 13,323,431 | $27.7M | 4.7% |
| GMED GLOBUS MED INC | 301,816 | $23.8M | 4.1% |
| GSK GSK PLC | 436,700 | $22.9M | 3.9% |
| TYRA TYRA BIOSCIENCES INC | 695,315 | $22.2M | 3.8% |
| WAY WAYSTAR HLDG CORP | 925,834 | $19.0M | 3.3% |
| IDYA IDEAYA BIOSCIENCES INC | 480,383 | $17.9M | 3.1% |
| ORKA ORUKA THERAPEUTICS INC | 177,118 | $16.9M | 2.9% |
| CI THE CIGNA GROUP | 57,750 | $15.9M | 2.7% |
| SNY SANOFI SA | 364,200 | $15.5M | 2.7% |
| ICLR ICON PUB LTD CO | 88,186 | $15.3M | 2.6% |
| VTRS VIATRIS INC | 954,299 | $15.2M | 2.6% |
| CCRN CROSS CTRY HEALTHCARE INC | 1,098,393 | $14.5M | 2.5% |
| RAPP RAPPORT THERAPEUTICS INC | 307,657 | $12.8M | 2.2% |
| ABT ABBOTT LABORATORIES | 128,656 | $11.7M | 2.0% |
| CELC CELCUITY INC | 110,022 | $11.5M | 2.0% |
| ZBH ZIMMER BIOMET HOLDINGS INC | 131,445 | $11.3M | 1.9% |
| REGN REGENERON PHARMACEUTICALS | 18,000 | $11.2M | 1.9% |
| BMY BRISTOL-MYERS SQUIBB CO | 193,500 | $11.1M | 1.9% |
| MDT MEDTRONIC PLC | 142,500 | $11.1M | 1.9% |
| VIR VIR BIOTECHNOLOGY INC | 1,075,274 | $11.0M | 1.9% |
| SENS SENSEONICS HLDGS INC | 1,592,692 | $9.0M | 1.6% |
| EYPT EYEPOINT INC | 623,130 | $8.9M | 1.5% |
SEC FORM 13F · Q2 2026 · VALUES AS REPORTED, NOT PRICES
New positions this quarter
Held at 2026-06-30, not at 2026-03-31 · 15 in all · reported value as of 2026-06-30
| Holding | Shares | Reported value | % of portfolio |
|---|---|---|---|
| ALLO ALLOGENE THERAPEUTICS INC | 13,323,431 | $27.7M | 4.7% |
| GMED GLOBUS MED INC | 301,816 | $23.8M | 4.1% |
| IDYA IDEAYA BIOSCIENCES INC | 480,383 | $17.9M | 3.1% |
| CI THE CIGNA GROUP | 57,750 | $15.9M | 2.7% |
| VTRS VIATRIS INC | 954,299 | $15.2M | 2.6% |
| REGN REGENERON PHARMACEUTICALS | 18,000 | $11.2M | 1.9% |
| BMY BRISTOL-MYERS SQUIBB CO | 193,500 | $11.1M | 1.9% |
| MDT MEDTRONIC PLC | 142,500 | $11.1M | 1.9% |
| CYBIN INC | 1,300,000 | $8.6M | 1.5% |
| TNGX TANGO THERAPEUTICS INC | 208,500 | $6.5M | 1.1% |
| AVAH AVEANNA HEALTHCARE HLDGS INC | 369,036 | $3.2M | 0.5% |
| AORT ARTIVION INC | 48,481 | $1.1M | 0.2% |
| NEUROONE MED TECHNOLOGIES CO | 82,767 | $251.6K | <0.1% |
| ENVB ENVERIC BIOSCIENCES INC | 180,000 | $248.4K | <0.1% |
| QTI QT IMAGING HLDGS INC | 15,236 | $62.0K | <0.1% |
Sold out
Held at 2026-03-31, gone by 2026-06-30 · 31 in all · reported value as of 2026-03-31
| Holding | Shares 2026-03-31 | Reported value | % of portfolio then |
|---|---|---|---|
| CORT CORCEPT THERAPEUTICS INC | 674,759 | $27.2M | 3.9% |
| LIVN LIVANOVA PLC | 421,615 | $26.8M | 3.9% |
| EMBC EMBECTA CORP | 1,847,850 | $16.3M | 2.4% |
| ABVX ABIVAX SA | 135,800 | $15.1M | 2.2% |
| HAE HAEMONETICS CORP MASS | 220,672 | $12.4M | 1.8% |
| TFX TELEFLEX INCORPORATED | 94,800 | $11.3M | 1.6% |
| BMRN BIOMARIN PHARMACEUTICAL INC | 194,226 | $11.0M | 1.6% |
| GPCR STRUCTURE THERAPEUTICS INC | 209,093 | $10.1M | 1.5% |
| BHVN BIOHAVEN LTD | 1,163,926 | $9.8M | 1.4% |
| MNPR MONOPAR THERAPEUTICS INC | 173,506 | $9.5M | 1.4% |
| CRNX CRINETICS PHARMACEUTICALS IN | 249,887 | $9.1M | 1.3% |
| EWTX EDGEWISE THERAPEUTICS INC | 268,986 | $8.5M | 1.2% |
| CMPS COMPASS PATHWAYS PLC | 1,506,525 | $8.3M | 1.2% |
| QDEL QUIDELORTHO CORP | 359,011 | $5.9M | 0.9% |
| REPL REPLIMUNE GROUP INC | 720,036 | $5.5M | 0.8% |
| OGN ORGANON & CO | 865,908 | $5.2M | 0.7% |
| IRON DISC MEDICINE INC | 65,203 | $4.2M | 0.6% |
| IART INTEGRA LIFESCIENCES HLDGS C | 383,140 | $3.6M | 0.5% |
| PROQR THERAPEUTICS N V | 1,954,715 | $3.2M | 0.5% |
| SI SHOULDER INNOVATIONS INC | 210,641 | $3.1M | 0.4% |
| KYMR KYMERA THERAPEUTICS INC | 32,235 | $2.7M | 0.4% |
| CNTX CONTEXT THERAPEUTICS INC | 917,922 | $2.4M | 0.3% |
| HYPR HYPERFINE INC | 1,000,000 | $1.1M | 0.2% |
| FHTX FOGHORN THERAPEUTICS INC | 122,889 | $587.4K | <0.1% |
| TERNS PHARMACEUTICALS INC | 10,100 | $532.5K | <0.1% |
Biggest increases and decreases
Positions held at both quarter ends, by change in shares · reported value as of 2026-06-30
Increases
| Holding | Shares 2026-03-31 | Shares 2026-06-30 | Change | Reported value |
|---|---|---|---|---|
| COR CENCORA INC | 100,894 | 173,588 | +72.0% | $49.1M |
| SENS SENSEONICS HLDGS INC | 115,784 | 1,592,692 | +1,275.6% | $9.0M |
| ZBH ZIMMER BIOMET HOLDINGS INC | 62,613 | 131,445 | +109.9% | $11.3M |
| SNY SANOFI SA | 239,671 | 364,200 | +52.0% | $15.5M |
| ORKA ORUKA THERAPEUTICS INC | 132,496 | 177,118 | +33.7% | $16.9M |
| TYRA TYRA BIOSCIENCES INC | 605,439 | 695,315 | +14.8% | $22.2M |
| GSK GSK PLC | 385,879 | 436,700 | +13.2% | $22.9M |
| AVR ANTERIS TECHNOLOGIES GLOBAL | 5,382,965 | 5,545,984 | +3.0% | $54.6M |
| RLMD RELMADA THERAPEUTICS INC | 965,000 | 1,003,562 | +4.0% | $6.9M |
| SVRA SAVARA INC | 613,888 | 617,675 | +0.6% | $3.8M |
Decreases
| Holding | Shares 2026-03-31 | Shares 2026-06-30 | Change | Reported value |
|---|---|---|---|---|
| ICLR ICON PUB LTD CO | 306,358 | 88,186 | -71.2% | $15.3M |
| DNTH DIANTHUS THERAPEUTICS INC | 370,045 | 59,254 | -84.0% | $5.8M |
| WAY WAYSTAR HLDG CORP | 1,642,236 | 925,834 | -43.6% | $19.0M |
| ANIP ANI PHARMACEUTICALS INC | 265,543 | 97,305 | -63.4% | $8.1M |
| CELC CELCUITY INC | 193,843 | 110,022 | -43.2% | $11.5M |
| SION SIONNA THERAPEUTICS INC | 294,340 | 127,808 | -56.6% | $5.6M |
| ABT ABBOTT LABORATORIES | 186,574 | 128,656 | -31.0% | $11.7M |
| VIR VIR BIOTECHNOLOGY INC | 1,498,620 | 1,075,274 | -28.2% | $11.0M |
| OCUL OCULAR THERAPEUTIX INC | 968,597 | 539,493 | -44.3% | $5.3M |
| ZBIO ZENAS BIOPHARMA INC | 331,730 | 208,557 | -37.1% | $5.3M |
| MMS MAXIMUS INC | 768,825 | 715,267 | -7.0% | $38.5M |
| RAPP RAPPORT THERAPEUTICS INC | 366,809 | 307,657 | -16.1% | $12.8M |
CIK 1482416 · 13F FILINGS ON EDGAR · INFORMATIONAL ONLY
