Avidity Partners Management LP 13F holdings
Avidity Partners Management LP reported 45 positions with a total reported value of $624.4M as of 2026-06-30, in its 13F for Q2 2026, filed 2026-08-14. Top holdings by reported value: DNTH DIANTHUS THERAPEUTICS INC (32.8%), CGON CG ONCOLOGY INC (15.9%), ORKA ORUKA THERAPEUTICS INC (11.6%), JBIO JADE BIOSCIENCES INC (6.1%), ELVN ENLIVEN THERAPEUTICS INC (4.5%). Against 2026-03-31 it opened 7 new positions and exited 14. Next 13F due by 2026-11-14, the legal deadline 45 days after the quarter ending 2026-09-30.
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Top holdings
25 largest of 45 positions · reported value as of 2026-06-30
| Holding | Shares | Reported value | % of portfolio |
|---|---|---|---|
| DNTH DIANTHUS THERAPEUTICS INC | 2,104,184 | $205.1M | 32.8% |
| CGON CG ONCOLOGY INC | 1,398,948 | $99.4M | 15.9% |
| ORKA ORUKA THERAPEUTICS INC | 760,424 | $72.4M | 11.6% |
| JBIO JADE BIOSCIENCES INC | 1,700,708 | $37.8M | 6.1% |
| ELVN ENLIVEN THERAPEUTICS INC | 550,000 | $27.9M | 4.5% |
| CATX PERSPECTIVE THERAPEUTICS INC | 6,299,999 | $21.5M | 3.4% |
| AKTS AKTIS ONCOLOGY INC | 484,200 | $15.6M | 2.5% |
| PVLA PALVELLA THERAPEUTICS INC NE | 70,000 | $10.7M | 1.7% |
| MOBI MOBIA MED INC | 798,282 | $10.7M | 1.7% |
| RGEN REPLIGEN CORP | 77,800 | $10.6M | 1.7% |
| IMUX IMMUNIC INC | 669,941 | $10.3M | 1.6% |
| SENS SENSEONICS HLDGS INC | 1,600,000 | $9.1M | 1.5% |
| KPTI KARYOPHARM THERAPEUTICS INC | 924,487 | $9.0M | 1.4% |
| TEVA TEVA PHARMACEUTICAL INDS LTD | 200,000 | $6.8M | 1.1% |
| DXCM DEXCOM INC | 100,000 | $6.7M | 1.1% |
| TEM TEMPUS AI INC | 105,000 | $6.1M | 1.0% |
| MDT MEDTRONIC PLC | 70,000 | $5.5M | 0.9% |
| VIR VIR BIOTECHNOLOGY INC | 519,300 | $5.3M | 0.8% |
| GPCR STRUCTURE THERAPEUTICS INC | 98,000 | $5.3M | 0.8% |
| EHC ENCOMPASS HEALTH CORP | 42,000 | $4.2M | 0.7% |
| TENX TENAX THERAPEUTICS INC | 265,934 | $3.9M | 0.6% |
| NVCT NUVECTIS PHARMA INC | 200,000 | $3.7M | 0.6% |
| PODD INSULET CORP | 24,000 | $3.7M | 0.6% |
| BSX BOSTON SCIENTIFIC CORP | 80,000 | $3.4M | 0.5% |
| MSLE SATELLOS BIOSCIENCE INC | 387,769 | $3.0M | 0.5% |
SEC FORM 13F · Q2 2026 · VALUES AS REPORTED, NOT PRICES
New positions this quarter
Held at 2026-06-30, not at 2026-03-31 · 7 in all · reported value as of 2026-06-30
| Holding | Shares | Reported value | % of portfolio |
|---|---|---|---|
| MOBI MOBIA MED INC | 798,282 | $10.7M | 1.7% |
| SENS SENSEONICS HLDGS INC | 1,600,000 | $9.1M | 1.5% |
| NVCT NUVECTIS PHARMA INC | 200,000 | $3.7M | 0.6% |
| ALMR ALAMAR BIOSCIENCES INC | 110,000 | $3.0M | 0.5% |
| AVLN AVALYN PHARMACEUTICALS INC | 60,000 | $2.0M | 0.3% |
| KLRA KAILERA THERAPEUTICS INC | 80,000 | $1.8M | 0.3% |
| EVMN EVOMMUNE INC | 75,000 | $996.8K | 0.2% |
Sold out
Held at 2026-03-31, gone by 2026-06-30 · 14 in all · reported value as of 2026-03-31
| Holding | Shares 2026-03-31 | Reported value | % of portfolio then |
|---|---|---|---|
| HUM HUMANA INC | 25,000 | $5.9M | 0.6% |
| ICLR ICON PLC | 32,000 | $3.7M | 0.4% |
| NTRA NATERA INC | 18,000 | $3.7M | 0.4% |
| HIMS HIMS & HERS HEALTH INC | 125,000 | $2.9M | 0.3% |
| CORT CORCEPT THERA | 60,000 | $2.6M | 0.3% |
| CNC CENTENE CORP | 70,000 | $2.3M | 0.2% |
| AVR ANTERIS TECHNOLOGIES GLOBAL | 300,000 | $1.8M | 0.2% |
| MLTX MOONLAKE IMMUNOTHERAPEUTICS | 100,000 | $1.8M | 0.2% |
| KVUE KENVUE INC ORD | 100,000 | $1.7M | 0.2% |
| RVMD REVOLUTION MEDICINES INC | 15,000 | $1.5M | 0.2% |
| ABVX ABIVAX SA-ADR | 10,000 | $1.1M | 0.1% |
| ABUS ARBUTUS BIOPHARMA CORP | 250,000 | $1.1M | 0.1% |
| UNH UNITEDHEALTH GRP | 3,800 | $1.0M | 0.1% |
| ACAD ACADIA PHARM | 25,934 | $579.8K | <0.1% |
Biggest increases and decreases
Positions held at both quarter ends, by change in shares · reported value as of 2026-06-30
Increases
| Holding | Shares 2026-03-31 | Shares 2026-06-30 | Change | Reported value |
|---|---|---|---|---|
| CGON CG ONCOLOGY INC | 1,288,948 | 1,398,948 | +8.5% | $99.4M |
| PODD INSULET CORP | 10,000 | 24,000 | +140.0% | $3.7M |
| GPCR STRUCTURE THERAPEUTICS INC | 78,000 | 98,000 | +25.6% | $5.3M |
| TEM TEMPUS AI INC | 90,000 | 105,000 | +16.7% | $6.1M |
Decreases
| Holding | Shares 2026-03-31 | Shares 2026-06-30 | Change | Reported value |
|---|---|---|---|---|
| DNTH DIANTHUS THERAPEUTICS INC | 4,208,368 | 2,104,184 | -50.0% | $205.1M |
| IMUX IMMUNIC INC | 7,369,352 | 669,941 | -90.9% | $10.3M |
| ORKA ORUKA THERAPEUTICS INC | 1,520,848 | 760,424 | -50.0% | $72.4M |
| JBIO JADE BIOSCIENCES INC | 2,801,416 | 1,700,708 | -39.3% | $37.8M |
| CATX PERSPECTIVE THERAPEUTICS INC | 12,099,998 | 6,299,999 | -47.9% | $21.5M |
| SCYX SCYNEXIS INC | 4,163,320 | 260,206 | -93.8% | $1.1M |
| TEVA TEVA PHARMACEUTICAL INDS LTD | 650,100 | 200,000 | -69.2% | $6.8M |
| AKTS AKTIS ONCOLOGY INC | 937,132 | 484,200 | -48.3% | $15.6M |
| ELVN ENLIVEN THERAPEUTICS INC | 800,000 | 550,000 | -31.2% | $27.9M |
| VIR VIR BIOTECHNOLOGY INC | 1,569,300 | 519,300 | -66.9% | $5.3M |
| PVLA PALVELLA THERAPEUTICS INC NE | 140,000 | 70,000 | -50.0% | $10.7M |
| RGEN REPLIGEN CORP | 155,600 | 77,800 | -50.0% | $10.6M |
CIK 1791827 · 13F FILINGS ON EDGAR · INFORMATIONAL ONLY
